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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">957</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2020-16-1-106-113</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Molecular subtypes of bladder cancer and first success in personalized treatment</article-title><trans-title-group xml:lang="ru"><trans-title>Молекулярные подтипы рака мочевого пузыря и первые успехи в персонализированном лечении.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7877-8344</contrib-id><name-alternatives><name xml:lang="en"><surname>Osetnik</surname><given-names>V. K.</given-names></name><name xml:lang="ru"><surname>Осетник</surname><given-names>В. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>154, Fontanka River Embankment, Saint Petersburg 190103</italic></p></bio><bio xml:lang="ru"><p>Клиника высоких медицинских технологий им. Н.И. Пирогова</p><p><italic>190103 Санкт-Петербург,набережная реки Фонтанки, 154</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mamizhev</surname><given-names>E. M.</given-names></name><name xml:lang="ru"><surname>Мамижев</surname><given-names>Э. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>154, Fontanka River Embankment, Saint Petersburg 190103</italic></p></bio><bio xml:lang="ru"><p><bold>Эльдар Мухамедович Мамижев,<italic> </italic></bold>врач онколог, онкологического отделения с хирургическим блоком </p><p><italic>190103 Санкт-Петербург,набережная реки Фонтанки, 154</italic></p></bio><email>mamijev@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dzalilov</surname><given-names>I. B.</given-names></name><name xml:lang="ru"><surname>Джалилов</surname><given-names>И. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>154, Fontanka River Embankment, Saint Petersburg 190103</italic></p></bio><bio xml:lang="ru"><p><italic>190103 Санкт-Петербург,набережная реки Фонтанки, 154</italic></p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Artemyeva</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Артемьева</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>68 Leningradskaya St., Pesochniji, Saint Petersburg 197758</italic></p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4608-9349</contrib-id><name-alternatives><name xml:lang="en"><surname>Kushnarev</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Кушнарев</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochniji, Saint Petersburg 197758</p></bio><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg State University Hospital</institution></aff><aff><institution xml:lang="ru">Клиника высоких технологий им. Н. И. Пирогова Санкт-Петербургского государственного университета</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Saint Petersburg State University Hospital</institution></aff><aff><institution xml:lang="ru">НИИ онкологии им.Н.Н.Петрова</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-03-30" publication-format="electronic"><day>30</day><month>03</month><year>2020</year></pub-date><volume>16</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>106</fpage><lpage>113</lpage><history><date date-type="received" iso-8601-date="2019-06-19"><day>19</day><month>06</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-08-09"><day>09</day><month>08</month><year>2019</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/957">https://oncourology.abvpress.ru/oncur/article/view/957</self-uri><abstract xml:lang="en"><p><italic>In the literature review we described studies, the main purpose of which was to distribute bladder tumors by molecular subtypes. A similar classification has long been actively used in the treatment of breast cancer. The pioneering work in the molecular subtypes of bladder cancer includes the work by Lund group, the TCGA (The Cancer Genome Atlas) project, the MD Anderson study. We have also included data on attempts to apply molecular taxonomy of bladder cancer in treatment.</italic></p></abstract><trans-abstract xml:lang="ru"><p><italic>В представленном обзоре литературы рассмотрены исследования, основной целью которых было распределить опухоли мочевого пузыря по молекулярным подтипам. Схожая классификация уже давно активно используется при лечении рака молочной железы. К основополагающим работам в области молекулярных подтипов рака мочевого пузыря относятся исследования группы Лунда, проект TCGA, ислледования MD Anderson. Также, мы включили данные о попытках применения молекулярной таксономии рака мочевого пузыря в лечении.  </italic></p></trans-abstract><kwd-group xml:lang="en"><kwd>bladder cancer</kwd><kwd>molecular subtype</kwd><kwd>bladder cancer treatment</kwd><kwd>immunohistochemistry</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак мочевого пузыря</kwd><kwd>молекулярные подтипы</kwd><kwd>лечение рака мочевого пузыря</kwd><kwd>имуногистохимия</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">нет</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Kirkali, Ziya, et al. "Bladder cancer: epidemiology, staging and grading, and diagnosis." Urology 66.6 (2005): 4-34.</mixed-citation><mixed-citation xml:lang="ru">Kirkali Z., Chan T., Manoharan M. et al. Bladder cancer: epidemiology, staging and grading, and diagnosis. Urology 2005;66(6):4–34. 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