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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">888</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2019-15-1-101-107</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. URINARY BLADDER CANCER</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак мочевого пузыря</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The first experience of using obturator nerve block to prevent spasm of adductor muscles of the thigh during transurethral resection of bladder</article-title><trans-title-group xml:lang="ru"><trans-title>Первый опыт применения блокады запирательного нерва в целях предотвращения спазма приводящих мышц бедра при трансуретральной резекции мочевого пузыря</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6608-1163</contrib-id><name-alternatives><name xml:lang="en"><surname>Rychkov</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Рычков</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>Иван Анатольевич Рычков - врач анестезиолог-реаниматолог отделения анестезиологии-реанимации.</p><p>115478 Москва, Каширское шоссе, 24</p><p>SPIN-код: 5397-8851</p></bio><email>ivanmma@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6503-4322</contrib-id><name-alternatives><name xml:lang="en"><surname>Garyaev</surname><given-names>R. V.</given-names></name><name xml:lang="ru"><surname>Гаряев</surname><given-names>Р. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7748-9527</contrib-id><name-alternatives><name xml:lang="en"><surname>Matveev</surname><given-names>V. B.</given-names></name><name xml:lang="ru"><surname>Матвеев</surname><given-names>В. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1258-0922</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernyaev</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Черняев</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-03-30" publication-format="electronic"><day>30</day><month>03</month><year>2019</year></pub-date><volume>15</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>101</fpage><lpage>107</lpage><history><date date-type="received" iso-8601-date="2018-11-14"><day>14</day><month>11</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2019-01-23"><day>23</day><month>01</month><year>2019</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/888">https://oncourology.abvpress.ru/oncur/article/view/888</self-uri><abstract xml:lang="en"><p><bold>The objective</bold> is to study the possibility of using the obturator nerve block under the control of nerve stimulator to prevent the thigh adductor muscles spasm during transurethral resection of bladder tumor.</p><p><bold>Materials and methods</bold>. The prospective randomized study included data obtained during the surgical treatment of 50patients with lateral wall bladder tumor, which was subjected transurethral resection of the bladder. In the GA group (n = 25) was performed general anesthesia with use muscle relaxants, in the NS group (n = 25) spinal anesthesia was performed in combination with obturator nerve block by 10 ml of a 2 % solution of lidocaine under the control of nerve stimulation.</p><p><bold>Results.</bold> The thigh adductor muscles spasm was observed in 5 cases (25 %) in the GA group and in 3 cases (12 %) in the NS group (p = 0.702), this was the cause of bladder perforation in 1 (4 %) patient in the NS group. The incidence of arterial hypotension in the NS group was lower than in the GA group (0 % versus 32 %; p = 0.004), as well as the incidence of sinus bradycardia (12 % versus 48 %; p = 0.012). The time of being in operating room in the NS group was 45 minutes (40; 53) versus 60 minutes (50; 85) in the GA group (p = 0.006).</p><p><bold>Conclusion</bold>. The spinal anesthesia in combination with obturator nerve block under the control of nerve stimulation, as well as the general anesthesia with use muscle relaxants did not guarantee the absence of adductor muscles spasm during transurethral resection of the lateral wall bladder. The obturator nerve block under the control of nerve stimulation only can not be recommended to prevent perforation of the bladder wall in these interventions.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования</bold> — изучение возможности применения блокады запирательного нерва под контролем нейростимулятора для предупреждения спазма приводящих мышц бедра при трансуретральной резекции мочевого пузыря.</p><p><bold>Материалы и методы</bold>. В проспективное рандомизированное исследование включены данные, полученные при хирургическом лечении 50 больных, которым в связи с новообразованием, расположенным на боковой стенке мочевого пузыря, была выполнена трансуретральная резекция мочевого пузыря. Пациентам контрольной группы (группа ОА; n = 25) проводили общую анестезию с использованием миорелаксантов, исследуемой группы (группа НС; n = 25) — спинальную анестезию в сочетании с блокадой запирательного нерва 2 % раствором лидокаина 10 мл под контролем нейростимуляции.</p><p><bold>Результаты</bold>. Спазм приводящих мышц бедра отмечался у 5 (20 %) пациентов группы ОА и 3 (12 %) группы НС (р = 0,702), что стало причиной перфорации мочевого пузыря у 1 (4 %) больного группы НС. Частота артериальной гипотензии в группе НС была ниже, чем в группе ОА (0 % против 32 %; p = 0,004), также как и частота синусовой брадикардии (12 % против 48 %; p = 0,012). Время нахождения в операционной в группе НС составило 45мин (40; 53) против 60 мин (50; 85) в группе ОА (р = 0,006).</p><p><bold>Заключение.</bold> Спинальная анестезия с блокадой запирательного нерва под контролем нейростимуляции, как и общая анестезия с мышечными релаксантами, не гарантировала отсутствие спазма приводящих мышц бедра во время резекции боковой стенки мочевого пузыря. Блокада запирательного нерва только под контролем нейростимуляции не может быть рекомендована для предупреждения перфорации стенки мочевого пузыря при данных вмешательствах.</p></trans-abstract><kwd-group xml:lang="en"><kwd>perforation of bladder</kwd><kwd>obturator nerve block</kwd><kwd>obturator reflex</kwd><kwd>adductor muscle spasm</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>перфорация мочевого пузыря</kwd><kwd>блокада запирательного нерва</kwd><kwd>рефлекс запирательного нерва</kwd><kwd>спазм приводящих мышц бедра</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1.	Garcia Rodriguez J., Jalon Monzon A., Gonzalez Alvarez R.C. et al. An alternative technique to prevent of obturator nerve stimulation during lateral bladder tumors transurethral resection. Actas Urol Esp 2005;29(5):445—7. PMID: 16013788.</mixed-citation><mixed-citation xml:lang="ru">Garcia Rodriguez J., Jalon Monzon A., Gonzalez Alvarez R.C. et al. An alternative technique to prevent of obturator nerve stimulation during lateral bladder tumors transurethral resection. Actas Urol Esp 2005;29(5):445—7. PMID: 16013788.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2.	Kuo J.Y. Prevention of obturator jerk during transurethral resection of bladder tumor. JTUA 2008;19:27-31.</mixed-citation><mixed-citation xml:lang="ru">Kuo J.Y. Prevention of obturator jerk during transurethral resection of bladder tumor. JTUA 2008;19:27-31.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3.	Bolat D., Aydogdu O., Tekgul Z.T. et al. Impact of nerve stimulator-guided obturator nerve block on the short-term outcomes and complications of transurethral resection of bladder tumor: A prospective randomized controlled study. Can Urol Assoc J 2015;9(11—12):780—4. DOI: 10.5489/cuaj.3149. PMID: 26600884.</mixed-citation><mixed-citation xml:lang="ru">Bolat D., Aydogdu O., Tekgul Z.T. et al. Impact of nerve stimulator-guided obturator nerve block on the short-term outcomes and complications of transurethral resection of bladder tumor: A prospective randomized controlled study. Can Urol Assoc J 2015;9(11—12):780—4. DOI: 10.5489/cuaj.3149. PMID: 26600884.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4.	Chen W.M., Cheng C.L., Yang C.R., Chung V. Surgical tip to prevent bladder perforation during transurethral resection of bladder tumors. Urology 2008;72(3):667—8. DOI: 10.1016/j.urol-ogy.2008.04.042. PMID: 18597827.</mixed-citation><mixed-citation xml:lang="ru">Chen W.M., Cheng C.L., Yang C.R., Chung V. Surgical tip to prevent bladder perforation during transurethral resection of bladder tumors. Urology 2008;72(3):667—8. DOI: 10.1016/j.urol-ogy.2008.04.042. PMID: 18597827.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5.	Walsh C.P. Surgical treatment of bladder cancer. In: Campbell’s urology. 9th ed. Eds.: B.A. Retik, D.E. Vaughan, A.J. Wein. Philadelphia: Saunders, 2007. Pp. 2819—2823.</mixed-citation><mixed-citation xml:lang="ru">Walsh C.P. Surgical treatment of bladder cancer. In: Campbell’s urology. 9th ed. Eds.: B.A. Retik, D.E. Vaughan, A.J. Wein. Philadelphia: Saunders, 2007. Pp. 2819—2823.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6.	Yildirim I., Basal S., Irkilata H.C. et al. Safe resection of bladder tumors with plasma kinetic energy. UHOD 2009;19:232—6.</mixed-citation><mixed-citation xml:lang="ru">Yildirim I., Basal S., Irkilata H.C. et al. Safe resection of bladder tumors with plasma kinetic energy. UHOD 2009;19:232—6.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7.	So P.C. Two case reports of obturator nerve block for transurethral resection of bladder tumor. Hong Kong Med J 2004;10(1): 57—9. PMID: 14967858.</mixed-citation><mixed-citation xml:lang="ru">So P.C. Two case reports of obturator nerve block for transurethral resection of bladder tumor. Hong Kong Med J 2004;10(1): 57—9. PMID: 14967858.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8.	Honglin W. The research of intravenous injection of vecuronium in preventing obturator nerve reflex in the transurethral resection of bladder tumor of the lateral wall bladder tumor. J Mudanj Med Univers 2013;3:21—3.</mixed-citation><mixed-citation xml:lang="ru">Honglin W. The research of intravenous injection of vecuronium in preventing obturator nerve reflex in the transurethral resection of bladder tumor of the lateral wall bladder tumor. J Mudanj Med Univers 2013;3:21—3.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><mixed-citation>Fujimoto M., Kawano K., Yamamoto T. The adequate rocuronium dose required for complete block of the adductor muscles of the thigh. Acta Anaesthesiol Scand 2017;62(3):304—11. DOI: 10.1111/ aas.13045. PMID: 29178460.</mixed-citation></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10.	Ong E.L., Chan S.T. Transurethral surgery and the adductor spasm. Ann Acad Med Singapore 2000;29(2):259-62. PMID: 10895352.</mixed-citation><mixed-citation xml:lang="ru">Ong E.L., Chan S.T. Transurethral surgery and the adductor spasm. Ann Acad Med Singapore 2000;29(2):259-62. PMID: 10895352.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11.	Pladzyk K., Jureczko L., Lazowski T. Over 500 obturator nerve blocks in the lithotomy position during transurethral resection of bladder tumor. Cent European J Urol 2012;65(2);67—70. DOI: 10.5173/ceju.2012.02.art2. PMID: 24578931.</mixed-citation><mixed-citation xml:lang="ru">Pladzyk K., Jureczko L., Lazowski T. Over 500 obturator nerve blocks in the lithotomy position during transurethral resection of bladder tumor. Cent European J Urol 2012;65(2);67—70. DOI: 10.5173/ceju.2012.02.art2. PMID: 24578931.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12.	Di Benedetto P., Pinto G., Arcioni R. et al. Anatomy and imaging of lumbar plexus. Minerva Anestesiol 2005;71(9):549-54. PMID: 16166916.</mixed-citation><mixed-citation xml:lang="ru">Di Benedetto P., Pinto G., Arcioni R. et al. Anatomy and imaging of lumbar plexus. Minerva Anestesiol 2005;71(9):549-54. PMID: 16166916.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13.	Akkaya T., Comert A., Kendir S. et al. Detailed anatomy of accessory obturator nerve blockade. Minerva Anestesiol 2008;74(4):119—22. PMID: 18354367.</mixed-citation><mixed-citation xml:lang="ru">Akkaya T., Comert A., Kendir S. et al. Detailed anatomy of accessory obturator nerve blockade. Minerva Anestesiol 2008;74(4):119—22. PMID: 18354367.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14.	Vloka J.D., Hadzic A. Obturator and genitofemoral nerve blocks. Tech Reg Anesth Pain Manag 1999;3(1):28—32.</mixed-citation><mixed-citation xml:lang="ru">Vloka J.D., Hadzic A. Obturator and genitofemoral nerve blocks. Tech Reg Anesth Pain Manag 1999;3(1):28—32.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15.	Akata T., Murakami J., Yoshinaga A. Life-threatening haemorrhage following obturator artery injury during transurethral bladder surgery: a sequel of an unsuccessful obturator nerve block. Acta Anaesthe-siol Scand 1999;43(7):784-8. PMID: 10456822.</mixed-citation><mixed-citation xml:lang="ru">Akata T., Murakami J., Yoshinaga A. Life-threatening haemorrhage following obturator artery injury during transurethral bladder surgery: a sequel of an unsuccessful obturator nerve block. Acta Anaesthe-siol Scand 1999;43(7):784-8. PMID: 10456822.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16.	Moningi S., Durga P., Ramachandran G. et al. Comparison of inguinal versus classic approach for obturator nerve block in patients undergoing transurethral resection of bladder tumors under spinal anesthesia. J Anaesthesiol Clin Pharmacol 2014;30(1):41—5. DOI: 10.4103/0970-9185.125702. PMID: 24574592.</mixed-citation><mixed-citation xml:lang="ru">Moningi S., Durga P., Ramachandran G. et al. Comparison of inguinal versus classic approach for obturator nerve block in patients undergoing transurethral resection of bladder tumors under spinal anesthesia. J Anaesthesiol Clin Pharmacol 2014;30(1):41—5. DOI: 10.4103/0970-9185.125702. PMID: 24574592.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17.	Patel D., Shah B., Patel B.M. Obturator nerve block for bladder tumours. Indian J Anaesth 2004;48(1):47-9.</mixed-citation><mixed-citation xml:lang="ru">Patel D., Shah B., Patel B.M. Obturator nerve block for bladder tumours. Indian J Anaesth 2004;48(1):47-9.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18.	Yoshida T., Onishi T., Furutani K., Baba H. A new ultrasound-guided pubic approach for proximal obturator nerve block: clinical study and cadaver evaluation. Anaesthesia 2016;71(3):291—7. DOI: 10.1111/anae.13336. PMID: 26620274.</mixed-citation><mixed-citation xml:lang="ru">Yoshida T., Onishi T., Furutani K., Baba H. A new ultrasound-guided pubic approach for proximal obturator nerve block: clinical study and cadaver evaluation. Anaesthesia 2016;71(3):291—7. DOI: 10.1111/anae.13336. PMID: 26620274.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
