<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">652</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2017-13-3-124-131</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Is there an association between prostate cancer and human papillomaviruses? Returning to the unresolved problem</article-title><trans-title-group xml:lang="ru"><trans-title>Ассоциирован ли рак предстательной железы с вирусами папилломы человека? Возвращаясь к нерешенной проблеме</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volgareva</surname><given-names>G. M.</given-names></name><name xml:lang="ru"><surname>Волгарева</surname><given-names>Г. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478, Russia</p></bio><bio xml:lang="ru"><p>ведущий научный сотрудник, лаб. механизмов гибели опухолевых клеток НИИ Канцерогенеза,доктор биологических наук, доцент</p><p>Россия, 115478 Москва, Каширское шоссе, 24</p></bio><email>galina.volgareva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N. N. Blokhin National Medical Research Oncology Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-09-30" publication-format="electronic"><day>30</day><month>09</month><year>2017</year></pub-date><volume>13</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>124</fpage><lpage>131</lpage><history><date date-type="received" iso-8601-date="2017-01-31"><day>31</day><month>01</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-08-24"><day>24</day><month>08</month><year>2017</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/652">https://oncourology.abvpress.ru/oncur/article/view/652</self-uri><abstract xml:lang="en"><p>Prostate cancer morbidity and mortality rates are steadily increasing in Russia and the world. The etiology of this cancer has not been adequately studied. In particular, the role of high-risk human papillomavirus types that are potent biological carcinogens in a number of other human organs remains unclear. Different laboratories worldwide continue to provide information, the authors of which make mutually exclusive conclusions regarding the involvement of these viruses in the genesis of prostate cancer. This review contains an analysis of the data available in the literature on the possible involvement of human papillomaviruses in prostate cancer.</p></abstract><trans-abstract xml:lang="ru"><p>Заболеваемость раком предстательной железы и смертность от данного заболевания неуклонно возрастают. Этиология этой формы рака недостаточно изучена. Остается неясной роль вирусов папилломы человека типов высокого онкогенного риска, которые в ряде других органов человека являются сильными биологическими канцерогенами. Продолжают появляться сообщения из разных лабораторий мира, авторы которых делают взаимоисключающие выводы относительно участия этих вирусов в генезе рака предстательной железы. Обзор содержит анализ данных литературы, опубликованных преимущественно в последние годы, о возможном участии вирусов папилломы человека в возникновении рака предстательной железы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prostate</kwd><kwd>cancer</kwd><kwd>human papillomavirus</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>предстательная железа</kwd><kwd>рак</kwd><kwd>вирус папилломы человека</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Torre L. A., Siegel R. L., Ward E. M., Jemal A. Global cancer incidence and mortality rates and trends – an update. Cancer Epidemiol Biomarkers Prev 2016;25(1):16–27. DOI: 10.1158/1055–9965.EPI-15–0578. PMID: 26667886.</mixed-citation><mixed-citation xml:lang="ru">Torre L. A., Siegel R. L., Ward E. M., Jemal A. Global cancer incidence and mortality rates and trends – an update. Cancer Epidemiol Biomarkers Prev 2016;25(1):16–27. DOI: 10.1158/1055–9965.EPI-15–0578. PMID: 26667886.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Имянитов Е. Н. Эпидемиология и биология рака простаты. Практическая онкология 2008;9(2):57–64. [Imyaitov E. N. Epidemiology and biology of prostate cancer. Prakticheskaya onkologiya = Practical Oncology 2008;9(2):57–64. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Имянитов Е. Н. Эпидемиология и биология рака простаты. Практическая онкология 2008;9(2):57–64. [Imyaitov E. N. Epidemiology and biology of prostate cancer. Prakticheskaya onkologiya = Practical Oncology 2008;9(2):57–64. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Schröder F. H., Roobol M. J. Prostate cancer epidemic in sight? Eur Urol 2012;61(6):1093– 5. DOI: 10.1016/j.eururo.2012.03.019. PMID: 22464308.</mixed-citation><mixed-citation xml:lang="ru">Schröder F. H., Roobol M. J. Prostate cancer epidemic in sight? Eur Urol 2012;61(6):1093– 5. DOI: 10.1016/j.eururo.2012.03.019. PMID: 22464308.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Злокачественные новообразования в России в 2014 году (заболеваемость и смертность). Под ред. А. Д. Каприна, В. В. Старинского, Г. В. Петровой. М.: МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. 250 с. [Malignant tumors in Russia in 2015 (morbidity and fatality). Eds.: А. D. Kaprin, V. V. Starinskiy, G. V. Petrova. Moscow: MNIOI im. P. A. Gertsena – filial FGBU “NMIRTS” Minzdrava Rossii, 2017. 250 p. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2014 году (заболеваемость и смертность). Под ред. А. Д. Каприна, В. В. Старинского, Г. В. Петровой. М.: МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. 250 с. [Malignant tumors in Russia in 2015 (morbidity and fatality). Eds.: А. D. Kaprin, V. V. Starinskiy, G. V. Petrova. Moscow: MNIOI im. P. A. Gertsena – filial FGBU “NMIRTS” Minzdrava Rossii, 2017. 250 p. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Заридзе Д. Г. Профилактика рака. М.: ИМА-ПРЕСС, 2009. 224 с. [Zaridze D. G. Prophylaxis of cancer. Мoscow: IMA-PRESS, 2009. 224 p. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Заридзе Д. Г. Профилактика рака. М.: ИМА-ПРЕСС, 2009. 224 с. [Zaridze D. G. Prophylaxis of cancer. Мoscow: IMA-PRESS, 2009. 224 p. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002;2(5): 342–50. DOI: 10.1038/nrc798. PMID: 12044010.</mixed-citation><mixed-citation xml:lang="ru">zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002;2(5): 342–50. DOI: 10.1038/nrc798. PMID: 12044010.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. zur Hausen H. To vaccination and beyond. Biochemistry (Mosc) 2008;73(5):498–503. PMID: 18605974.</mixed-citation><mixed-citation xml:lang="ru">zur Hausen H. To vaccination and beyond. Biochemistry (Mosc) 2008;73(5):498–503. PMID: 18605974.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Hrbacek J., Urban M., Hamsikova E. et al. Serum antibodies against genitourinary infectious agents in prostate cancer and benign prostate hyperplasia patients: a case- control study. BMC Cancer 2011;3(11):53. DOI: 10.1186/1471-2407-11-53. PMID: 21291519.</mixed-citation><mixed-citation xml:lang="ru">Hrbacek J., Urban M., Hamsikova E. et al. Serum antibodies against genitourinary infectious agents in prostate cancer and benign prostate hyperplasia patients: a case- control study. BMC Cancer 2011;3(11):53. DOI: 10.1186/1471-2407-11-53. PMID: 21291519.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. IARC Monographs on the evaluation of carcinogenic risks to humans. Human papillomaviruses. Lyon, 2007. Vol. 90. 689 p.</mixed-citation><mixed-citation xml:lang="ru">IARC Monographs on the evaluation of carcinogenic risks to humans. Human papillomaviruses. Lyon, 2007. Vol. 90. 689 p.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. IARC Monographs on the evaluation of carcinogenic risks to humans. A review of human carcinogens. Part B. Biological agents. Lyon, 2011. Vol. 100. 502 p.</mixed-citation><mixed-citation xml:lang="ru">IARC Monographs on the evaluation of carcinogenic risks to humans. A review of human carcinogens. Part B. Biological agents. Lyon, 2011. Vol. 100. 502 p.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Ruijter E., van de Kaa C., Miller G. et al. Molecular genetics and epidemiology of prostate carcinoma. Endocr Rev 1999;20(1):22–45. DOI: 10.1210/edrv.20.1.0356. PMID: 10047972.</mixed-citation><mixed-citation xml:lang="ru">Ruijter E., van de Kaa C., Miller G. et al. Molecular genetics and epidemiology of prostate carcinoma. Endocr Rev 1999;20(1):22–45. DOI: 10.1210/edrv.20.1.0356. PMID: 10047972.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Zambrano A., Kalantari M., Simoneau A. et al. Detection of human polyomaviruses and papillomaviruses in prostatic tissue reveals the prostate as a habitat for multiple viral infections. Prostate 2002;53(4):263–76. DOI: 10.1002/pros.10157. PMID: 12430138.</mixed-citation><mixed-citation xml:lang="ru">Zambrano A., Kalantari M., Simoneau A. et al. Detection of human polyomaviruses and papillomaviruses in prostatic tissue reveals the prostate as a habitat for multiple viral infections. Prostate 2002;53(4):263–76. DOI: 10.1002/pros.10157. PMID: 12430138.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Taylor M. L., Mainous A. G., Wells B. J. Prostate cancer and sexually transmitted diseases: a meta-analysis. Fam Med 2005;37(7):506–12. PMID: 15988645.</mixed-citation><mixed-citation xml:lang="ru">Taylor M. L., Mainous A. G., Wells B. J. Prostate cancer and sexually transmitted diseases: a meta-analysis. Fam Med 2005;37(7):506–12. PMID: 15988645.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Волгарева Г.М. Ассоциирован ли рак предстательной железы с вирусами папилломы человека? Российский биотерапевтический журнал 2017;16(2):6–12. [Volgareva G.M. Is there an association between prostate cancer and human papillomaviruses? Russiyskiy bioterapevticheskiy zhurnal = Journal of Biotherapy 2017;16(2):6–12. (In Russ.)]. DOI: 10.17650/1726-9776-2017-13-3-00-00.</mixed-citation><mixed-citation xml:lang="ru">Волгарева Г.М. Ассоциирован ли рак предстательной железы с вирусами папилломы человека? Российский биотерапевтический журнал 2017;16(2):6–12. [Volgareva G.M. Is there an association between prostate cancer and human papillomaviruses? Russiyskiy bioterapevticheskiy zhurnal = Journal of Biotherapy 2017;16(2):6–12. (In Russ.)]. DOI: 10.17650/1726-9776-2017-13-3-00-00.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Kasiske B. L., Snyder J. J., Gilbertson D. T., Wang C. Cancer after kidney transplantation in the United States. Am J Transplant 2004;4(6):905–13. DOI: 10.1111/j.1600-6143.2004.00450.x. PMID: 15147424.</mixed-citation><mixed-citation xml:lang="ru">Kasiske B. L., Snyder J. J., Gilbertson D. T., Wang C. Cancer after kidney transplantation in the United States. Am J Transplant 2004;4(6):905–13. DOI: 10.1111/j.1600-6143.2004.00450.x. PMID: 15147424.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Grulich A. E., van Leeuwen M. T., Falster M. O., Vajdic C. M. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 2007;370(9581):59–67. DOI: 10.1016/S0140–6736(07)61050–2. PMID: 17617273.</mixed-citation><mixed-citation xml:lang="ru">Grulich A. E., van Leeuwen M. T., Falster M. O., Vajdic C. M. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 2007;370(9581):59–67. DOI: 10.1016/S0140–6736(07)61050–2. PMID: 17617273.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Collett D., Mumford L., Banner N. R. et al. Comparison of the incidence of malignancy in recipients of different types of organ: a UK Registry audit. Am J Transplant 2010;10(8):1889–96. DOI: 10.1111/j.1600–6143.2010.03181.x. PMID: 20659094.</mixed-citation><mixed-citation xml:lang="ru">Collett D., Mumford L., Banner N. R. et al. Comparison of the incidence of malignancy in recipients of different types of organ: a UK Registry audit. Am J Transplant 2010;10(8):1889–96. DOI: 10.1111/j.1600–6143.2010.03181.x. PMID: 20659094.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18. Engels E. A., Pfeiffer R. M., Fraumeni J. F. Jr et al. Spectrum of cancer risk among US solid organ transplant recipients. JAMA 2011;306(17):1891–901. DOI: 10.1001/jama.2011.1592. PMID: 22045767.</mixed-citation><mixed-citation xml:lang="ru">Engels E. A., Pfeiffer R. M., Fraumeni J. F. Jr et al. Spectrum of cancer risk among US solid organ transplant recipients. JAMA 2011;306(17):1891–901. DOI: 10.1001/jama.2011.1592. PMID: 22045767.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19. Leiros G. J., Galliano S. R., Sember M. E. et al. Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina. BMC Urol 2005;24(5):15. DOI: 10.1186/1471-2490-5-15. PMID: 16307686.</mixed-citation><mixed-citation xml:lang="ru">Leiros G. J., Galliano S. R., Sember M. E. et al. Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina. BMC Urol 2005;24(5):15. DOI: 10.1186/1471-2490-5-15. PMID: 16307686.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20. Martinez-Fierro M. L., Leach R. J., Gomez-Guerra L. S. et al. Identification of viral infections in the prostate and evaluation of their association with cancer. BMC Cancer 2010;10:326. DOI: 10.1186/1471-2407-10-326. PMID: 20576103.</mixed-citation><mixed-citation xml:lang="ru">Martinez-Fierro M. L., Leach R. J., Gomez-Guerra L. S. et al. Identification of viral infections in the prostate and evaluation of their association with cancer. BMC Cancer 2010;10:326. DOI: 10.1186/1471-2407-10-326. PMID: 20576103.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21. Deschoolmeester V., van Marck V., Baay M. et al. Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer. BMC Cancer 2010;10:117. DOI: 10.1186/1471-2407-10- 117. PMID: 20346145.</mixed-citation><mixed-citation xml:lang="ru">Deschoolmeester V., van Marck V., Baay M. et al. Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer. BMC Cancer 2010;10:117. DOI: 10.1186/1471-2407-10- 117. PMID: 20346145.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">22. Golovina D. A., Trofimova O. B., Ermilova V. D. et al. Complex of molecular genetic and immunohistochemical methods for detection of human papillomavirus in the bladder cancer epithelium. Bull Exp Biol Med 2014;157(1):70–3. DOI: 10.1007/s10517-014-2494-0. PMID: 24909719.</mixed-citation><mixed-citation xml:lang="ru">Golovina D. A., Trofimova O. B., Ermilova V. D. et al. Complex of molecular genetic and immunohistochemical methods for detection of human papillomavirus in the bladder cancer epithelium. Bull Exp Biol Med 2014;157(1):70–3. DOI: 10.1007/s10517-014-2494-0. PMID: 24909719.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">23. Smelov V., Eklund C., Bzhalava D. et al. Expressed prostate secretions in the study of human papillomavirus epidemiology in the male. PLoS One 2013;8(6):625–30. DOI: 10.1371/journal.pone.0066630. PMID: 23799125.</mixed-citation><mixed-citation xml:lang="ru">Smelov V., Eklund C., Bzhalava D. et al. Expressed prostate secretions in the study of human papillomavirus epidemiology in the male. PLoS One 2013;8(6):625–30. DOI: 10.1371/journal.pone.0066630. PMID: 23799125.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">24. Singh N., Hussain S., Kakkar N. et al. Implication of high risk human papillomavirus HR- HPV infection in prostate cancer in Indian population – a pioneering case-control analysis. Sci Rep 2015;5:7822. DOI: 10.1038/srep07822. PMID: 25592643.</mixed-citation><mixed-citation xml:lang="ru">Singh N., Hussain S., Kakkar N. et al. Implication of high risk human papillomavirus HR- HPV infection in prostate cancer in Indian population – a pioneering case-control analysis. Sci Rep 2015;5:7822. DOI: 10.1038/srep07822. PMID: 25592643.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">25. Yow M. A., Tabrizi S. N., Severi G. et al. Detection of infectious organisms in archival prostate cancer tissues. BMC Cancer 2014;14:579. DOI: 10.1186/1471-2407-14-579. PMID: 25106851.</mixed-citation><mixed-citation xml:lang="ru">Yow M. A., Tabrizi S. N., Severi G. et al. Detection of infectious organisms in archival prostate cancer tissues. BMC Cancer 2014;14:579. DOI: 10.1186/1471-2407-14-579. PMID: 25106851.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">26. Yow M. A., Tabrizi S. N., Severi G. et al. Characterization of microbial communities with aggressive prostate cancer tissues. Infect Agent Cancer 2017;12:4. DOI: 10.1186/s13027- 016-0112-7. PMID: 28101126.</mixed-citation><mixed-citation xml:lang="ru">Yow M. A., Tabrizi S. N., Severi G. et al. Characterization of microbial communities with aggressive prostate cancer tissues. Infect Agent Cancer 2017;12:4. DOI: 10.1186/s13027- 016-0112-7. PMID: 28101126.</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">27. Pascale M., Pracella D., Barbazza R. et al. Is human papillomavirus associated with prostate cancer survival? Dis Markers 2013;35(6):607–13. DOI: 10.1155/2013/735843. PMID: 24288430.</mixed-citation><mixed-citation xml:lang="ru">Pascale M., Pracella D., Barbazza R. et al. Is human papillomavirus associated with prostate cancer survival? Dis Markers 2013;35(6):607–13. DOI: 10.1155/2013/735843. PMID: 24288430.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">28. Faoro V., Barbazza R., Bonin S. et al. Detection of HPV E7 oncoviral protein in cervical lesions by a new antibody. Appl Immunohistochem Mol Morphol 2013;21(4);341–50. DOI: 10.1097/PAI. 0b013e318269bf5d. PMID: 22935825.</mixed-citation><mixed-citation xml:lang="ru">Faoro V., Barbazza R., Bonin S. et al. Detection of HPV E7 oncoviral protein in cervical lesions by a new antibody. Appl Immunohistochem Mol Morphol 2013;21(4);341–50. DOI: 10.1097/PAI. 0b013e318269bf5d. PMID: 22935825.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">29. Montironi R., Mazzuccheli R., Scarpelli M. et al. Gleason grading of prostate cancer in needle biopsies or radical prostatectomy specimens: contemporary approach, current clinical significance and sourses of pathology discrepancies. BJU Int 2005;95(8):1146–52. DOI: 10.1111/j. 1464-410X.2005.05540.x. PMID: 15877724.</mixed-citation><mixed-citation xml:lang="ru">Montironi R., Mazzuccheli R., Scarpelli M. et al. Gleason grading of prostate cancer in needle biopsies or radical prostatectomy specimens: contemporary approach, current clinical significance and sourses of pathology discrepancies. BJU Int 2005;95(8):1146–52. DOI: 10.1111/j. 1464-410X.2005.05540.x. PMID: 15877724.</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">30. Thompson I. M., Ankerst D. P., Chi C. et al. Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial. J Natl Cancer Inst 2006;98(8):529–34. DOI: 10.1093/jnci/djj131. PMID: 16622122.</mixed-citation><mixed-citation xml:lang="ru">Thompson I. M., Ankerst D. P., Chi C. et al. Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial. J Natl Cancer Inst 2006;98(8):529–34. DOI: 10.1093/jnci/djj131. PMID: 16622122.</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">31. Dillner J., Knekt P., Boman J. et al. Seroepidemiological association between human- papillomavirus infection and risk of prostate cancer. Int J Cancer 1998;75(4):564–7. PMID: 9466657.</mixed-citation><mixed-citation xml:lang="ru">Dillner J., Knekt P., Boman J. et al. Seroepidemiological association between human- papillomavirus infection and risk of prostate cancer. Int J Cancer 1998;75(4):564–7. PMID: 9466657.</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">32. Adami H. O., Kuper H., Andersson S. O. et al. Prostate cancer risk and serologic evidence of human papilloma virus infection: a population-based case control study. Cancer Epidemol Biomarkers Prev 2003;12(9):872–5. PMID: 14504197.</mixed-citation><mixed-citation xml:lang="ru">Adami H. O., Kuper H., Andersson S. O. et al. Prostate cancer risk and serologic evidence of human papilloma virus infection: a population-based case control study. Cancer Epidemol Biomarkers Prev 2003;12(9):872–5. PMID: 14504197.</mixed-citation></citation-alternatives></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">33. Korodi Z., Dillner J., Jellum E. et al. Human papillomavirus 16, 18 and 33 infections and risk of prostate cancer: a Nordic nested case control study. Cancer Epidemiol Biomarkers Prev 2005;14(12):2952–5. DOI: 10.1158/1055–9965.EPI-05–0602. PMID: 16365015.</mixed-citation><mixed-citation xml:lang="ru">Korodi Z., Dillner J., Jellum E. et al. Human papillomavirus 16, 18 and 33 infections and risk of prostate cancer: a Nordic nested case control study. Cancer Epidemiol Biomarkers Prev 2005;14(12):2952–5. DOI: 10.1158/1055–9965.EPI-05–0602. PMID: 16365015.</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><citation-alternatives><mixed-citation xml:lang="en">34. Sitas F., Urban M., Stein L. et al. The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population. Infect Agent Cancer 2007;2:6. DOI: 10.1186/1750-9378-2-6. PMID: 17331260.</mixed-citation><mixed-citation xml:lang="ru">Sitas F., Urban M., Stein L. et al. The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population. Infect Agent Cancer 2007;2:6. DOI: 10.1186/1750-9378-2-6. PMID: 17331260.</mixed-citation></citation-alternatives></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">35. Sutcliffe S., Viscidi R. P., Till C. et al. Human papillomavirus types 16, 18 and 31 serostatus and prostate cancer risk in the Prostate Cancer Trial. Cancer Epidemiol Biomarkers Prev 2010;19(2):614–8. DOI: 10.1158/1055–9965.EPI-09–1080. PMID: 20142255.</mixed-citation><mixed-citation xml:lang="ru">Sutcliffe S., Viscidi R. P., Till C. et al. Human papillomavirus types 16, 18 and 31 serostatus and prostate cancer risk in the Prostate Cancer Trial. Cancer Epidemiol Biomarkers Prev 2010;19(2):614–8. DOI: 10.1158/1055–9965.EPI-09–1080. PMID: 20142255.</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">36. Franco E. L., Villa L. L., Sobrinho J. P. et al. Epidemiology of acquisition and clearance of cervical human papilloma infection in women from a high-risk area for cervical cancer. J Infect Dis 1999;180(5):1415–23. DOI: 10.1086/315086. PMID: 10515798.</mixed-citation><mixed-citation xml:lang="ru">Franco E. L., Villa L. L., Sobrinho J. P. et al. Epidemiology of acquisition and clearance of cervical human papilloma infection in women from a high-risk area for cervical cancer. J Infect Dis 1999;180(5):1415–23. DOI: 10.1086/315086. PMID: 10515798.</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><citation-alternatives><mixed-citation xml:lang="en">37. Zumbach K., Kisseljov F., Sacharova O. et al. Antibodies against oncoproteins E6 and E7 of human papillomavirus types 16 and 18 in cervical-carcinoma patients from Russia. Int J Cancer 2000;85(3):313–8. PMID: 10652419.</mixed-citation><mixed-citation xml:lang="ru">Zumbach K., Kisseljov F., Sacharova O. et al. Antibodies against oncoproteins E6 and E7 of human papillomavirus types 16 and 18 in cervical-carcinoma patients from Russia. Int J Cancer 2000;85(3):313–8. PMID: 10652419.</mixed-citation></citation-alternatives></ref><ref id="B38"><label>38.</label><citation-alternatives><mixed-citation xml:lang="en">38. Gillison M. L., Shah K. V. Role of mucosal human papillomavirus in nongenital cancers. J Natl Cancer Inst Monogr 2003;31:57–65. PMID: 12807947.</mixed-citation><mixed-citation xml:lang="ru">Gillison M. L., Shah K. V. Role of mucosal human papillomavirus in nongenital cancers. J Natl Cancer Inst Monogr 2003;31:57–65. PMID: 12807947.</mixed-citation></citation-alternatives></ref><ref id="B39"><label>39.</label><citation-alternatives><mixed-citation xml:lang="en">39. Weijerman P. C., König J. J., Wong S. T. et al. Lipofection-mediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA. Cancer Res 1994;54(21):5579–83. PMID: 7923200.</mixed-citation><mixed-citation xml:lang="ru">Weijerman P. C., König J. J., Wong S. T. et al. Lipofection-mediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA. Cancer Res 1994;54(21):5579–83. PMID: 7923200.</mixed-citation></citation-alternatives></ref><ref id="B40"><label>40.</label><citation-alternatives><mixed-citation xml:lang="en">40. Weijerman P. C., van Drunen E., König J. J. et al. Specific cytogenetic aberrations in two novel human prostatic cell lines immortalized by human papillomavirus type 18 DNA. Cancer Genet Cytoge net 1997;99(2):108–15. PMID: 9398864.</mixed-citation><mixed-citation xml:lang="ru">Weijerman P. C., van Drunen E., König J. J. et al. Specific cytogenetic aberrations in two novel human prostatic cell lines immortalized by human papillomavirus type 18 DNA. Cancer Genet Cytoge net 1997;99(2):108–15. PMID: 9398864.</mixed-citation></citation-alternatives></ref><ref id="B41"><label>41.</label><citation-alternatives><mixed-citation xml:lang="en">41. Weijerman P. C., Zhang Y., Shen J. et al. Expression of prostatic factors measured by reverse transcription polymerase chain reaction in human papillomavirus type 18 deoxyribonucleic acid immortalized prostate cell lines. Urology 1998;51(4):657–62. PMID: 9586625.</mixed-citation><mixed-citation xml:lang="ru">Weijerman P. C., Zhang Y., Shen J. et al. Expression of prostatic factors measured by reverse transcription polymerase chain reaction in human papillomavirus type 18 deoxyribonucleic acid immortalized prostate cell lines. Urology 1998;51(4):657–62. PMID: 9586625.</mixed-citation></citation-alternatives></ref><ref id="B42"><label>42.</label><citation-alternatives><mixed-citation xml:lang="en">42. Hartwig S., Syrjanen S., Dominiak-Felden G. et al. Estimation of the epidemiological burden of human papillomavirusrelated cancers and nonmalignant diseases in men in Europe. BMC Cancer 2012;12:30. DOI: 10.1186/1471-2407-12-30. PMID: 22260541.</mixed-citation><mixed-citation xml:lang="ru">Hartwig S., Syrjanen S., Dominiak-Felden G. et al. Estimation of the epidemiological burden of human papillomavirusrelated cancers and nonmalignant diseases in men in Europe. BMC Cancer 2012;12:30. DOI: 10.1186/1471-2407-12-30. PMID: 22260541.</mixed-citation></citation-alternatives></ref><ref id="B43"><label>43.</label><citation-alternatives><mixed-citation xml:lang="en">43. Reiter P. L., Pendergraft W. F., Brewer N. T. Meta-analysis of human papillomavirus infection concordance. Cancer Epidemiol Biomarkers Prev 2010;19(11):2916–31. DOI: 10.1158/1055-9965.EPI-10-0576. PMID: 20833971.</mixed-citation><mixed-citation xml:lang="ru">Reiter P. L., Pendergraft W. F., Brewer N. T. Meta-analysis of human papillomavirus infection concordance. Cancer Epidemiol Biomarkers Prev 2010;19(11):2916–31. DOI: 10.1158/1055-9965.EPI-10-0576. PMID: 20833971.</mixed-citation></citation-alternatives></ref><ref id="B44"><label>44.</label><citation-alternatives><mixed-citation xml:lang="en">44. de Lima Rocha M. G., Faria F. L., Goncalves L. et al. Prevalence of DNA-HPV in male sexual partners of HPV infected women and concordance of viral types in infected couples. PLoS One 2012;7(7):40988. DOI: 10.1371/journal.pone.0040988. PMID: 22815888.</mixed-citation><mixed-citation xml:lang="ru">de Lima Rocha M. G., Faria F. L., Goncalves L. et al. Prevalence of DNA-HPV in male sexual partners of HPV infected women and concordance of viral types in infected couples. PLoS One 2012;7(7):40988. DOI: 10.1371/journal.pone.0040988. PMID: 22815888.</mixed-citation></citation-alternatives></ref><ref id="B45"><label>45.</label><citation-alternatives><mixed-citation xml:lang="en">45. Foresta C., Garolla A., Zuccarello D. et al. Human papillomavirus found in sperm head of young adult males affects the progressive motility. Fertil Steril 2010;93(3):802–6. DOI: 10.1016/j.fertnstert.2008.10.050. PMID: 19100537.</mixed-citation><mixed-citation xml:lang="ru">Foresta C., Garolla A., Zuccarello D. et al. Human papillomavirus found in sperm head of young adult males affects the progressive motility. Fertil Steril 2010;93(3):802–6. DOI: 10.1016/j.fertnstert.2008.10.050. PMID: 19100537.</mixed-citation></citation-alternatives></ref><ref id="B46"><label>46.</label><citation-alternatives><mixed-citation xml:lang="en">46. Foresta C., Patassini C., Bertoldo A. et al. Mechanism of human papillomavirus binding to human spermatozoa and fertilizing ability of infected spermatozoa. PLoS One 2011;6(3):15036. DOI: 10.1371/journal.pone.0015036. PMID: 21408100.</mixed-citation><mixed-citation xml:lang="ru">Foresta C., Patassini C., Bertoldo A. et al. Mechanism of human papillomavirus binding to human spermatozoa and fertilizing ability of infected spermatozoa. PLoS One 2011;6(3):15036. DOI: 10.1371/journal.pone.0015036. PMID: 21408100.</mixed-citation></citation-alternatives></ref><ref id="B47"><label>47.</label><citation-alternatives><mixed-citation xml:lang="en">47. Yang Y., Jia C. W., Ma Y. M. et al. Correlation between HPV sperm infection and male infertility. Asian J Androl 2013;15(4):529–32. DOI: 10.1038/aja.2013.3647. PMID: 23603919.</mixed-citation><mixed-citation xml:lang="ru">Yang Y., Jia C. W., Ma Y. M. et al. Correlation between HPV sperm infection and male infertility. Asian J Androl 2013;15(4):529–32. DOI: 10.1038/aja.2013.3647. PMID: 23603919.</mixed-citation></citation-alternatives></ref><ref id="B48"><label>48.</label><citation-alternatives><mixed-citation xml:lang="en">48. Yang L., Xie S., Feng X. et al. Worldwide prevalence of human papillomavirus and relative risk of prostate cancer: a meta-analysis. Sci Rep 2015;5:14667. DOI: 10.1038/srep14667. PMID: 26441160.</mixed-citation><mixed-citation xml:lang="ru">Yang L., Xie S., Feng X. et al. Worldwide prevalence of human papillomavirus and relative risk of prostate cancer: a meta-analysis. Sci Rep 2015;5:14667. DOI: 10.1038/srep14667. PMID: 26441160.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
