Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press5310.17650/1726-9776-2010-6-2-45-49PROSTATE CANCERРАК ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫCLINICAL STAGING OF CANCER OF THE PROSTATE DURING ITS PRIMARY BIOPSYКЛИНИЧЕСКОЕ СТАДИРОВАНИЕ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ ПРИ ЕЕ ПЕРВИЧНОЙ БИОПСИИPetrovS. B.ПетровС. Б.
Russian Federation
petrov@urology.spb.ruRakulS. A.РакулС. А.
Russian Federation
petrov@urology.spb.ruZhivovA. V.ЖивовА. В.
Russian Federation
petrov@urology.spb.ruEloyevR. A.ЕлоевР. А.
Russian Federation
petrov@urology.spb.ruPlekhanovA. Yu.ПлехановА. Ю.
Russian Federation
petrov@urology.spb.ruKharchenkoP. V.ХарченкоП. В.
Russian Federation
petrov@urology.spb.ruDepartment of Urology, Military Medical AcademyКафедра урологии Военно-медицинской академииAndros Medical CenterМедицинский центр «Андрос»Department of Urology, Military Medical AcademyМедицинский центр «Андрос»300620106245492507201425072014https://oncourology.abvpress.ru/oncur/article/view/53

Clinical staging of cancer is the important element of a diagnostic process that determines the nature and scope of therapeutic measures required for a patient. Objective: to assess the role of clinical, clinical laboratory, and morphological findings in the diagnosis of prostate cancer (PC) and to analyze the pattern of its clinical stages in patients having different levels of serum prostate-specific antigen (PSA) and the results of digital rectal examination (DRE) and ultrasound study (USS) of the gland. Subjects and methods. The examination and follow-up records were analyzed in 2579 males aged 38-88 years who had indications for primary puncture biopsy of the prostate. Results. PC was detected in 997 (38.66%) patients. Clinically localized adenocarcinoma was diagnosed in 50.85% of cases, locally advanced one being in 49.15%, including that with its invasion into the seminal vesicles in 8.73%. The findings of DRE and transrectal USS and serum PSA values allow one to substantially define the likely extent of cancer.

prostate cancerbiopsydigital rectal examinationtransrectal ultrasound studyрак предстательной железыбиопсияпальцевое ректальное исследованиетрансректальное ультразвуковое исследование1. Hernandez J., Thompson I.M. Prostatespecific antigen: a review of the validation of the most commonly used Cancer biomarker. Cancer 2004;101:894-904.Hernandez J., Thompson I.M. Prostatespecific antigen: a review of the validation of the most commonly used Cancer biomarker. Cancer 2004;101:894-904.2. Teahan S.J., Klotz L.H. Current role of prostate-specific antigen kinetics in managing patients with prostate cancer. Br J Urol Int 2006; 97: 451-5.Teahan S.J., Klotz L.H. Current role of prostate-specific antigen kinetics in managing patients with prostate cancer. Br J Urol Int 2006; 97: 451-5.3. Hodge K.K., McNeal J.E., Terris M.K.,Stamey T.A. Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol 1989;142:71-4.Hodge K.K., McNeal J.E., Terris M.K.,Stamey T.A. Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol 1989;142:71-4.4. Cooperberg M.R., Broering J.M.,Litwin M.S. et al. The contemporary management of prostate cancer in the United States: lessons from the cancer of the prostate strategic urologic research endeavor (CapSURE), a national disease registry. J Urol 2004;171(4):1393-401.Cooperberg M.R., Broering J.M.,Litwin M.S. et al. The contemporary management of prostate cancer in the United States: lessons from the cancer of the prostate strategic urologic research endeavor (CapSURE), a national disease registry. J Urol 2004;171(4):1393-401.5. Shah J.B., McKiernan J.M.,Elkin E.P. et al. Prostate biopsy patterns in the CaPSURE database: evolution with time and impact on outcome after prostatectomy. J Urol 2008;179(1):136-40.Shah J.B., McKiernan J.M.,Elkin E.P. et al. Prostate biopsy patterns in the CaPSURE database: evolution with time and impact on outcome after prostatectomy. J Urol 2008;179(1):136-40.6. Лоран О.Б. Рак простаты: современный взгляд на проблему. В кн.: Материалы XI съезда урологов России. М., 2007. с. 5-13.Лоран О.Б. Рак простаты: современный взгляд на проблему. В кн.: Материалы XI съезда урологов России. М., 2007. с. 5-13.7. Ильин К.А., Магер В.О., Завацкий С.Е. и др. Анализ результатов биопсий пред-стательной железы в лечебных учрежде-ниях Екатеринбурга за 2000-2006 гг. Он-коурология 2008; (4):33-7.Ильин К.А., Магер В.О., Завацкий С.Е. и др. Анализ результатов биопсий пред-стательной железы в лечебных учрежде-ниях Екатеринбурга за 2000-2006 гг. Он-коурология 2008; (4):33-7.8. Sobin L.H., Wittekind C. TNM classification of malignant tumours. 6th ed. Wiley, 2002.Sobin L.H., Wittekind C. TNM classification of malignant tumours. 6th ed. Wiley, 2002.