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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">487</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2015-11-3-46-49</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Paraneoplastic syndrome in urothelial carcinoma of the kidney: difficulty in diagnosis and deterioration in prognosis</article-title><trans-title-group xml:lang="ru"><trans-title>Паранеопластический синдром при уротелиальной карциноме почки: затруднение диагностики, ухудшение прогноза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mamaev</surname><given-names>I. E.</given-names></name><name xml:lang="ru"><surname>Мамаев</surname><given-names>И. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>dr.mamaev@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Seroukhov</surname><given-names>A. Yu.</given-names></name><name xml:lang="ru"><surname>Сероухов</surname><given-names>А. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Glinin</surname><given-names>K. I.</given-names></name><name xml:lang="ru"><surname>Глинин</surname><given-names>К. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pronkin</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Пронкин</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff5"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">1Department of Urology, City Clinical Hospital Twelve, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">Отделение урологии ГБУЗ «Городская клиническая больница № 12 Департамента здравоохранения города Москвы»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">26, Bakinskaya St., Moscow 115516, Russia&#13;
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Department of Urology, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Россия, 115516, Москва, ул. Бакинская, 26&#13;
&#13;
кафедра урологии ГБОУ ВПО «Российский национальный  исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">1, Ostrovityanov St., Moscow 117997, Russia</institution></aff><aff><institution xml:lang="ru">Россия, 117997, Москва, ул. Островитянова, 1</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">26, Bakinskaya St., Moscow 115516, Russia</institution></aff><aff><institution xml:lang="ru">Россия, 115516, Москва, ул. Бакинская, 26</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Department of Urology, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">кафедра урологии ГБОУ ВПО «Российский национальный  исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-09-30" publication-format="electronic"><day>30</day><month>09</month><year>2015</year></pub-date><volume>11</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>46</fpage><lpage>49</lpage><history><date date-type="received" iso-8601-date="2015-09-24"><day>24</day><month>09</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-09-24"><day>24</day><month>09</month><year>2015</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/487">https://oncourology.abvpress.ru/oncur/article/view/487</self-uri><abstract xml:lang="en"><p>Paraneoplastic syndrome is not a common concomitance of urothelial tumors. The literature describes a few tens of clinical cases in which urothelial cancer has become a cause of marked nonspecific tumor-associated reactions, associated with the presence of the tumor. Bladder tumors are at stake in all cases. The given clinical observation describes paraneoplastic manifestations in high-grade urothelial carcinoma of the kidney. It demonstrates difficulties in differential diagnosis and gives a retrospective estimate of diagnostic and therapeutic tactics.</p></abstract><trans-abstract xml:lang="ru"><p>Паранеопластический синдром не является частым спутником уротелиальных опухолей. В литературе описано несколько десятков клинических наблюдений, когда уротелиальный рак становился причиной выраженных неспецифических системных реакций, ассоциированных с наличием опухоли. Во всех случаях речь шла об опухолях мочевого пузыря. В представленном клиническом наблюдении описаны паранеопластические проявления при низкодифференцированной уротелиальной карциноме почки. Продемонстрированы сложности дифференциальной диагностики и дана ретроспективная оценка диагностической и лечебной тактики.</p></trans-abstract><kwd-group xml:lang="en"><kwd>paraneoplastic syndrome</kwd><kwd>urothelial cancer of the kidney</kwd><kwd>urothelial carcinoma of the kidney</kwd><kwd>kidney tumor</kwd><kwd>leukemoid reaction</kwd><kwd>computed tomography</kwd><kwd>Bellini duct carcinoma</kwd><kwd>differential diagnosis</kwd><kwd>kidney biopsy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>паранеопластический синдром</kwd><kwd>уротелиальный рак почки</kwd><kwd>уротелиальная карцинома почки</kwd><kwd>опухоль почки</kwd><kwd>лейкемоидная реакция</kwd><kwd>компьютерная томография</kwd><kwd>протоковая карцинома Беллини</kwd><kwd>дифференциальная диагностика</kwd><kwd>биопсия почки</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Дворецкий Л.И. 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