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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">454</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2015-11-2-55-60</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PROSTATE CANCER</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>РАК ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Estimation of the extent of local prostate cancer spread according to magnetic resonance imaging findings and clinical prognostic factors</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка степени местной распространенности рака предстательной железы по данным магнитно-резонансной томографии и клинических прогностических ф акторов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kazymov</surname><given-names>A. T.</given-names></name><name xml:lang="ru"><surname>Казымов</surname><given-names>А. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Isaev</surname><given-names>A. G.</given-names></name><name xml:lang="ru"><surname>Исаев</surname><given-names>И. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ali-zade</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Али-заде</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Guliev</surname><given-names>F. A.</given-names></name><name xml:lang="ru"><surname>Гулиев</surname><given-names>Ф. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Musaev</surname><given-names>T. N.</given-names></name><name xml:lang="ru"><surname>Мусаев</surname><given-names>Т. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Dr.teymur@box.az</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aliev</surname><given-names>A. R.</given-names></name><name xml:lang="ru"><surname>Алиев</surname><given-names>А. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Cancer Center</institution></aff><aff><institution xml:lang="ru">Национальный центр онкологии</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">79, Zardabi Gasanbek St., Baku, AZ1011, Azerbaijan Republic</institution></aff><aff><institution xml:lang="ru">Азербайджанская Республика, AZ1011, Баку, ул. Зардаби Гасанбека, 79</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-06-30" publication-format="electronic"><day>30</day><month>06</month><year>2015</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>55</fpage><lpage>60</lpage><history><date date-type="received" iso-8601-date="2015-06-19"><day>19</day><month>06</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-06-19"><day>19</day><month>06</month><year>2015</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/454">https://oncourology.abvpress.ru/oncur/article/view/454</self-uri><abstract xml:lang="en"><p>To estimate the extent of local tumor spread is a main goal in the diagnosis of prostate cancer (PC). The value of this criterion is that its clinical stage plays a key role in choosing a treatment policy. Overestimation of the clinical stage of cancer leads to the fact that specialists refuse radical and its underestimation gives rise to its recurrence. Our trial defined criteria for the diagnostic efficiency of magnetic resonance imaging (MRI) in 150 PC patients who had undergone radical prostatectomy. The findings were as follows: the diagnostic sensitivity of the method in determining the spread of the cancer beyond the organ was 76.8 %; its diagnostic specificity and accuracy were 80.2 and 78.7 %, respectively. The positive predictive value in detecting the extra-organ spread of the tumor was equal to 76.8 %; the negative predictive value was 80.2 %. A prognostic classification of a risk for locally advanced PS has been developed using the independent clinical and MRI signs found.</p></abstract><trans-abstract xml:lang="ru"><p>Оценка степени местной распространенности опухоли является основной задачей в диагностике рака предстательной железы (РПЖ). Ценность данного критерия заключается в том, что клиническая стадия играет ключевую роль в выборе тактики лечения. Завышение клинической стадии приводит к отказу специалистов от радикального лечения, а занижение – к рецидиву болезни. В нашем исследовании определены критерии диагностической эффективности магнитно-резонансной томографии (МРТ) у 150 больных РПЖ, которым была выполнена радикальная простатэктомия. Полученные результаты: диагностическая чувствительность метода в определении выхода рака за пределы органа составила 76,8 %, диагностическая специфичность – 80,2 %, точность – 78,7 %. Положительное предсказательное значение выявления экстраорганного распространения опухоли было равно 76,8 %, отрицательное предсказательное значение – 80,2 %. Разработана прогностическая классификация риска наличия местно-распространенного РПЖ на основании выявленных независимых клинических и МРТ-признаков.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prostate cancer</kwd><kwd>magnetic resonance imaging</kwd><kwd>radical prostatectomy</kwd><kwd>seminal vesicles</kwd><kwd>transrectal ultrasonography</kwd><kwd>endorectal coil</kwd><kwd>prognostic model</kwd><kwd>positive predictive value</kwd><kwd>negative predictive value</kwd><kwd>clinical stage</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак предстательной железы</kwd><kwd>магнитно-резонансная томография</kwd><kwd>радикальная простатэктомия</kwd><kwd>семенные пузырьки</kwd><kwd>трансректальное ультразвуковое исследование</kwd><kwd>эндоректальная катушка</kwd><kwd>прогностическая модель</kwd><kwd>положительное предсказательное значение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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