Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press32210.17650/1726-9776-2010-6-3-57-62REVIEWОБЗОРNEW METHODS FOR PREDICTING THE SENSITIVITY OF RENAL CANCER TO IMMUNOTHERAPY ON THE BASIS OF ANALYSIS OF MOLECULAR GENETIC CHARACTERISTICS OF A TUMORНОВЫЕ МЕТОДЫ ПРОГНОЗА ЧУВСТВИТЕЛЬНОСТИ РАКА ПОЧКИ К ИММУНОТЕРАПИИ НА ОСНОВЕ АНАЛИЗА МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИХ ХАРАКТЕРИСТИК ОПУХОЛИAivazovM. T.АйвазовМ. Т.
Russian Federation
kaprin@mail.ruBozhenkoV. K.БоженкоВ. К.
Russian Federation
kaprin@mail.ruKaprinA. D.КапринА. Д.
Russian Federation
kaprin@mail.ruRussian X-ray Radiology Research Center, Russian Agency for Medical Technologies, MoscowФГУ РНЦРР, Москва300920106357620608201406082014https://oncourology.abvpress.ru/oncur/article/view/322

The paper reviews the literature on the treatment of renal cancer, mainly on postoperative immunotherapy. It outlines a role of cytokines in tumor-immune system interaction, the prognostic value of the level of expression of each cytokine for both survival rates and the efficiency of immunotherapy, as well as the use of this information to develop new therapeutic approaches.

Приведен обзор литературы, посвещенный проблеме лечения рака почки, главным образом проведению послеоперационной иммунотерапии. Освещается роль цитокинов во взаимодействии опухоли и иммунной системы, определена прогностическая ценность величины экспрессии каждого цитокина в отношении как выживаемости пациента, так и эффективности иммунотерапии, а также использования этой информации для разработки новых терапевтических подходов.

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