<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1974</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2025-21-4-134-139</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical case of surgical treatment of metastatic germ cell tumor of the testicle with simultaneous prosthesis of the inferior vena cava and aorta</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай хирургического лечения метастатической формы герминогенной опухоли яичка с одномоментным протезированием нижней полой вены и аорты</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9642-8260</contrib-id><name-alternatives><name xml:lang="en"><surname>Churina</surname><given-names>Yuliya A.</given-names></name><name xml:lang="ru"><surname>Чурина</surname><given-names>Юлия Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6673-1603</contrib-id><name-alternatives><name xml:lang="en"><surname>Ivanchenko</surname><given-names>G. A.</given-names></name><name xml:lang="ru"><surname>Иванченко</surname><given-names>Г. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-4375-8847</contrib-id><name-alternatives><name xml:lang="en"><surname>Potanin</surname><given-names>V. O.</given-names></name><name xml:lang="ru"><surname>Потанин</surname><given-names>В. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9449-5945</contrib-id><name-alternatives><name xml:lang="en"><surname>Derinov</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Деринов</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1133-8106</contrib-id><name-alternatives><name xml:lang="en"><surname>Dzyundzya</surname><given-names>A. N.</given-names></name><name xml:lang="ru"><surname>Дзюндзя</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4094-8771</contrib-id><name-alternatives><name xml:lang="en"><surname>Tlisov</surname><given-names>B. M.</given-names></name><name xml:lang="ru"><surname>Тлисов</surname><given-names>Б. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-7725-8339</contrib-id><name-alternatives><name xml:lang="en"><surname>Nigamatullina</surname><given-names>A. R.</given-names></name><name xml:lang="ru"><surname>Нигаматуллина</surname><given-names>А. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5133-011X</contrib-id><name-alternatives><name xml:lang="en"><surname>Shchegelskiy</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Щегельский</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2746-5962</contrib-id><name-alternatives><name xml:lang="en"><surname>Bezrukov</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Безруков</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3904-6415</contrib-id><name-alternatives><name xml:lang="en"><surname>Komarov</surname><given-names>R. N.</given-names></name><name xml:lang="ru"><surname>Комаров</surname><given-names>Р. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7134-6821</contrib-id><name-alternatives><name xml:lang="en"><surname>Tsarkov</surname><given-names>P. V.</given-names></name><name xml:lang="ru"><surname>Царьков</surname><given-names>П. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>churina_yu_a@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenovskiy University)</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2026-03-16" publication-format="electronic"><day>16</day><month>03</month><year>2026</year></pub-date><volume>21</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>134</fpage><lpage>139</lpage><history><date date-type="received" iso-8601-date="2025-09-17"><day>17</day><month>09</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2026-01-15"><day>15</day><month>01</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Churina Y.A., Ivanchenko G.A., Potanin V.O., Derinov A.A., Dzyundzya A.N., Tlisov B.M., Nigamatullina A.R., Shchegelskiy V.V., Bezrukov E.A., Komarov R.N., Tsarkov P.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Чурина Ю.А., Иванченко Г.А., Потанин В.О., Деринов А.А., Дзюндзя А.Н., Тлисов Б.М., Нигаматуллина А.Р., Щегельский В.В., Безруков Е.А., Комаров Р.Н., Царьков П.В.</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Churina Y.A., Ivanchenko G.A., Potanin V.O., Derinov A.A., Dzyundzya A.N., Tlisov B.M., Nigamatullina A.R., Shchegelskiy V.V., Bezrukov E.A., Komarov R.N., Tsarkov P.V.</copyright-holder><copyright-holder xml:lang="ru">Чурина Ю.А., Иванченко Г.А., Потанин В.О., Деринов А.А., Дзюндзя А.Н., Тлисов Б.М., Нигаматуллина А.Р., Щегельский В.В., Безруков Е.А., Комаров Р.Н., Царьков П.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1974">https://oncourology.abvpress.ru/oncur/article/view/1974</self-uri><abstract xml:lang="en"><p>Germ cell tumors are malignant tumors that develop from germinal cells. Over 90 % of all germ cell tumors in men are represented by germ cell seminomas. The incidence of choriocarcinoma does not increase with age but reaches its peak among people aged 25 to 34 years. A clinical case of surgical treatment of metastatic testicular choriocarcinoma with simultaneous nephrectomy, retroperitoneal lymph node dissection, prosthesis of the inferior vena cava and the infrarenal aorta is presented. The most serious complication in this group of patients is prosthetic infection. The implemented stage-by-stage multidisciplinary treatment approach allowed to achieve a good oncological and functional result.</p></abstract><trans-abstract xml:lang="ru"><p>Герминогенные опухоли – злокачественные новообразования, развивающиеся из герминативных клеток. Более 90 % всех герминогенных опухолей у мужчин представлено опухолями яичка. Заболеваемость хориокарциномой не увеличивается с возрастом и достигает своего пика в возрасте от 25 до 34 лет. В статье представлен клинический случай хирургического лечения метастатической формы хориокарциномы яичка с нефрэктомией, удалением забрюшинных лимфатических узлов, одномоментным протезированием нижней полой вены и инфраренального отдела аорты. Наиболее грозным и частым осложнением у пациентов данной группы является инфицирование сосудистых протезов. Реализованный этапный мультидисциплинарный подход к лечению позволил добиться хорошего онкологического и функционального результата.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prosthesis</kwd><kwd>testicular tumor</kwd><kwd>nephrectomy</kwd><kwd>metastasis</kwd><kwd>retroperitoneal lymph node dissection</kwd><kwd>aorta</kwd><kwd>inferior vena cava</kwd><kwd>ileostomy</kwd><kwd>surgical treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>протезирование</kwd><kwd>опухоль яичка</kwd><kwd>нефрэктомия</kwd><kwd>метастаз</kwd><kwd>забрюшинная лимфаденэктомия</kwd><kwd>аорта</kwd><kwd>нижняя полая вена</kwd><kwd>илеостома</kwd><kwd>хирургическое лечение</kwd></kwd-group><funding-group><funding-statement xml:lang="en">нет</funding-statement><funding-statement xml:lang="ru">нет</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Rumyantsev A.A., Gladkov O.A., Matveev V.B. et al. Practical recommendations for the treatment of germ cell tumors in men. Zlokachestvennye opukholi = Malignant Tumors 2022;12(3s2–1): 627–58. (In Russ.). DOI: 10.18027/2224-5057-2022-12-3s2-627-658</mixed-citation><mixed-citation xml:lang="ru">Румянцев А.А., Гладков О.А., Матвеев В.Б. и др. Практические рекомендации по лечению герминогенных опухолей у мужчин. Злокачественные опухоли 2022;12(3s2–1):627–58. DOI: 10.18027/2224-5057-2022-12-3s2-627-658</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><mixed-citation>Coleman M.P., Estève J., Damiecki P. et al. Trends in cancer incidence and mortality. IARC Scientific Publications 1993;(121):1–806. DOI: 10.3109/9780415874984-2</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Winter C., Pfister D., Busch J. et al. Residual tumor size and IGCCCG risk classification predict additional vascular procedures in patients with germ cell tumors and residual tumor resection: a multicenter analysis of the German Testicular Cancer Study Group. Eur Urol 2012;61(2):403–9. DOI: 10.1016/j.eururo.2011.10.045</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Lavery H.J., Bahnson R.R., Sharp D.S., Pohar K.S. Management of the residual post-chemotherapy retroperitoneal mass in germ cell tumors. Ther Adv Urol 2009;1:199–207. DOI: 10.1177/1756287209350315</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Travis L.B., Feldman D.R., Fung C. et al. Adolescent and young adult germ cell tumors: epidemiology, genomics, treatment, and survivorship. JCO 2024;42:696–706. DOI: 10.1200/JCO.23.01099</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Evmorfopoulos K., Chasiotis G., Barbatis A. et al. Complete vascular replacement of the infrarenal inferior vena cava and abdominal aorta during post-chemotherapy retroperitoneal lymph node dissection for a non-seminomatous germ cell tumor. Cur Oncol 2023;30(6):5448–55. DOI: 10.3390/curroncol30060412</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Kinebuchi Y., Ogawa T., Kato H. et al. Testicular cancer with tumor thrombus extending to the inferior vena cava successfully removed using veno-venous bypass: a case report. Int J Urol 2007;14(5):458–60. DOI: 10.1111/j.1442-2042.2007.01757.x</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Heidenreich A., Thüer D., Polyakov S. Postchemotherapy retroperitoneal lymph node dissection in advanced germ cell tumours of the testis. Eur Urol 2008;53(2):260–74. DOI: 10.1016/j.eururo.2007.10.033</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Mosharafa A.A., Foster R.S., Koch M.O. et al. Complications of post-chemotherapy retroperitoneal lymph node dissection for testis cancer. J Urol 2004;171(5):1839–41. DOI: 10.1097/01.ju.0000120141.89737.90</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Johnson S.C., Smith Z.L., Nottingham C. et al. Clinical and radiographic predictors of great vessel resection or reconstruction during retroperitoneal lymph node dissection for testicular cancer. Urology 2019;123:186–90. DOI: 10.1016/j.urology.2018.08.028</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Caldarelli G., Minervini A., Guerra M. et al. Prosthetic replacement of the inferior vena cava and the iliofemoral vein for urologically related malignancies. BJU Int 2002;90(4):368–74. DOI: 10.1046/j.1464-410X.2002.02919.x</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Heidenreich A., Haidl F., Paffenholz P. et al. Surgical management of complex residual masses following systemic chemotherapy for metastatic testicular germ cell tumours. Ann Oncol 2017;28(2):362–7. DOI: 10.1093/annonc/mdw605</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Perera G.B., Fujitani R.M., Kubaska S.M. Aortic graft infection: update on management and treatment options. Vasc Endovascular Surg 2006;40(1):1–10. DOI: 10.1177/153857440604000101</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Bunt T.J. Vascular graft infections: an update. Cardiovasc Surg 2001;9(3):225–33. DOI: 10.1016/s0967-2109(00)00104-6</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Vogel T.R., Symons R., Flum D.R. The incidence and factors associated with graft infection after aortic aneurysm repair. J Vasc Surg 2008;47(2):264–9. DOI: 10.1016/j.jvs.2007.10.030</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Post I.C.J.H., Vos C.G. Systematic review and meta-analysis on the management of open abdominal aortic graft infections. Eur J Vasc Endovasc Surg 2019;58(2):258–81. DOI: 10.1016/j.ejvs.2019.03.013</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Wilson S.E. New alternatives in management of the infected vascular prosthesis. Surg Infect 2001;2(2):171–7. DOI: 10.1089/109629601750469492</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Valentine R.J. Diagnosis and management of aortic graft infection. Semin Vasc Surg 2001;14(4):292–301. DOI: 10.1053/svas.2001.27874</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Hasse B., Husmann L., Zinkernagel A. et al. Vascular graft infections. Swiss Med Wkly 2013;143:w13754. DOI: 10.4414/smw.2013.13754</mixed-citation></ref></ref-list></back></article>
