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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1831</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2024-20-4-90-97</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Recurrence of prostate cancer of rare location: magnetic resonance diagnosis and treatment. Clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Рецидив рака предстательной железы редкой локализации: магнитно-резонансная диагностика и лечение. Клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1641-6452</contrib-id><contrib-id contrib-id-type="spin">9556-6556</contrib-id><name-alternatives><name xml:lang="en"><surname>Solodkiy</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Солодкий</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Profsoyuznaya St., Moscow 117997</p></bio><bio xml:lang="ru"><p>Солодкий Владимир Алексеевич - академик РАН, профессор, заслуженный врач РФ, директор ФГБУ «РНЦРР» Минздрава России.</p><p>117997 Москва, ул. Профсоюзная, 86</p></bio><email>director@rncrr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2905-7735</contrib-id><contrib-id contrib-id-type="spin">8380-3919</contrib-id><name-alternatives><name xml:lang="en"><surname>Pavlov</surname><given-names>A. Yu.</given-names></name><name xml:lang="ru"><surname>Павлов</surname><given-names>А. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Profsoyuznaya St., Moscow 117997</p></bio><bio xml:lang="ru"><p>Павлов Андрей Юрьевич - д.м.н., профессор, заместитель директора ФГБУ «РНЦРР» Минздрава России.</p><p>117997 Москва, ул. Профсоюзная, 86</p></bio><email>vracheg@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8348-5143</contrib-id><contrib-id contrib-id-type="spin">3848-9432</contrib-id><name-alternatives><name xml:lang="en"><surname>Rebrikova</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Ребрикова</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Vera A. Rebrikova.</p><p>86 Profsoyuznaya St., Moscow 117997</p></bio><bio xml:lang="ru"><p>Ребрикова Вера Александровна - к.м.н., научный сотрудник НИО комплексной диагностики заболеваний и радиотерапии ФГБУ «РНЦРР» Минздрава России.</p><p>117997 Москва, ул. Профсоюзная, 86</p></bio><email>rebrikova_vera@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1647-6180</contrib-id><contrib-id contrib-id-type="spin">1559-1728</contrib-id><name-alternatives><name xml:lang="en"><surname>Tsibulskii</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Цыбульский</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Profsoyuznaya St., Moscow 117997</p></bio><bio xml:lang="ru"><p>Цыбульский Алексей Дмитриевич - д.м.н., ведущий научный сотрудник отделения онкоурологии ФГБУ «РНЦРР» МЗ РФ.</p><p>117997 Москва, ул. Профсоюзная, 86</p></bio><email>vracheg@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kriger</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Кригер</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Profsoyuznaya St., Moscow 117997</p></bio><bio xml:lang="ru"><p>Кригер Анна Валентиновна – клинический ординатор по специальности «рентгенология» ФГБУ «РНЦРР» Минздрава России.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Scientific Center of Roentgenradiology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российский научный центр рентгенорадиологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-01" publication-format="electronic"><day>01</day><month>12</month><year>2024</year></pub-date><volume>20</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>90</fpage><lpage>97</lpage><history><date date-type="received" iso-8601-date="2024-07-24"><day>24</day><month>07</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-12-03"><day>03</day><month>12</month><year>2024</year></date></history><permissions><copyright-year>2024</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1831">https://oncourology.abvpress.ru/oncur/article/view/1831</self-uri><abstract xml:lang="en"><p>Prostate cancer (PCa) is the second most common cancer in the world, with a steady increase in incidence every year. Regardless of the chosen treatment method for patients with localized PCa, the development of local relapse occurs in at least 15 % of cases. The key point in monitoring patients with PCa today is dynamic monitoring of prostate-specific antigen levels. When biochemical recurrence is detected, the subsequent diagnostic algorithm strategy should be aimed at visualizing the tumor site, which can be local, in the lymph nodes, or metastatic. Multiparametric magnetic resonance imaging can serve as a method for diagnosing and monitoring relapses of PCa located locally or in the lymph nodes of the pelvis. When assessing relapses located in the pelvic area, one should remember possible rare sites of their localization, as demonstrated in our clinical case. The optimal treatment for recurrent PCa is still controversial and requires further study.</p></abstract><trans-abstract xml:lang="ru"><p>Рак предстательной железы (РПЖ) занимает 2-е место по распространенности в мире, при этом ежегодно отмечается неуклонный рост заболеваемости. Независимо от выбранного метода лечения больных локализованным РПЖ развитие местного рецидива происходит не менее чем в 15 % случаев. Ключевым моментом в наблюдении за пациентами с РПЖ на сегодняшний день является динамический контроль уровня простатического специфического антигена. При выявлении биохимического рецидива стратегия последующего диагностического алгоритма должна быть направлена на визуализацию очага опухоли, который может быть локальным, в лимфатических узлах или метастатическим. Методом диагностики и наблюдения рецидивов РПЖ, расположенных локально или в лимфатических узлах таза, может служить мультипараметрическая магнитно-резонансная томография. При оценке рецидивов, расположенных в области малого таза, следует помнить о возможных редких местах их локализации, что продемонстрировано в нашем клиническом случае. Оптимальные методы лечения рецидивов РПЖ все еще остаются спорными и требуют дальнейшего изучения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prostate cancer</kwd><kwd>recurrence of prostate cancer</kwd><kwd>brachytherapy</kwd><kwd>multiparametric magnetic resonance imaging</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак предстательной железы</kwd><kwd>рецидив рака предстательной железы</kwd><kwd>брахитерапия</kwd><kwd>мультипараметрическая магнитно-резонансная томография</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Clinical guidelines. Prostate cancer. Ministry of Health of Russia, 2021–2022–2023 (20.01.2023). (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Клинические рекомендации. Рак предстательной железы. Минздрав России, 2021–2022–2023 (20.01.2023).</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Malignant tumors in Russia in 2023 (morbidity and mortality). Eds.: А.D. Kaprin, V.V. Starinskiy, A.O. Shakhzadova. Moscow: MNIOI im. P.A. Gertsena – filial FGBU “NMITS radiologii” Minzdrava Rossii, 2024. 276 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2023 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, О.В. Шахзадовой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2024. 276 с.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><mixed-citation>Sung H., Ferlay J., Siegel R.L. et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 2021;71(3):209–49. DOI: 10.3322/caac.21660</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Bergengren O., Pekala K.R., Matsoukas K. et al. 2022 Update on prostate cancer epidemiology and risk factors – a systematic review. Eur Urol 2023;84(2):191–206. DOI: 10.1016/j.eururo.2023.04.021</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Siegel D.A., O’Neil M.E., Richards T.B. et al. Prostate cancer incidence and survival, by stage and race/ethnicity – United States, 2001–2017. MMWR Morb Mortal Wkly Rep 2020;69(41):1473–80. DOI: 10.15585/mmwr.mm6941a1</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Mottet N., Bellmunt J., Bolla M. et al. EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: screening, diagnosis, and local treatment with curative intent. Eur Urol 2017;71(4):618–29. DOI: 10.1016/j.eururo.2016.08.003</mixed-citation></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Glybochko P.V., Alyaev Yu.G., Krupinov G.E. et al. Diagnosis and treatment of local recurrence of prostate cancer using hystoscanning and high-intensity focused ultrasound in patients after radical prostatectomy. Urologiia = Urology 2014;(5):72–6. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Глыбочко П.В., Аляев Ю.Г., Крупинов Г.Е. и др. Диагностика и лечение локального рецидива рака предстательной железы с использованием гистосканирования и высокоинтенсивного фокусированного ультразвука у пациентов после радикальной простатэктомии. Урология 2014;(5):72–6.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><mixed-citation>Artibani W., Porcaro A.B., De Marco V. et al. Management of biochemical recurrence after primary curative treatment for prostate cancer: a review. Urol Int 2018;100(3):251–62. DOI: 10.1159/000481438</mixed-citation></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Novikov R.V. Radioisotope lymphoscintigraphy in prostate cancer: a modern view on the problem. Eksperimental’naya i klinicheskaya urologiya = Experimental and Clinical Urology 2017;(2). Available at: https://cyberleninka.ru/article/n/radioizotopnaya-limfostsintigrafiya-pri-rake-predstatelnoy-zhelezy-sovremennyy-vzglyad-na-problemu (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Новиков Р.В. Радиоизотопная лимфосцинтиграфия при раке предстательной железы: современный взгляд на проблему. Экспериментальная и клиническая урология 2017;(2). Доступно по: https://cyberleninka.ru/article/n/radioizotopnaya-limfostsintigrafiya-pri-rake-predstatelnoy-zhelezy-sovremennyy-vzglyad-na-problemu</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><mixed-citation>Ploussard G., Fossati N., Wiegel T. et al. Management of persistently elevated prostate-specific antigen after radical prostatectomy: a systematic review of the literature. Eur Urol Oncol 2021;4(2):150–69. DOI: 10.1016/j.euo.2021.01.001</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Mohler J.L., Antonarakis E.S., Armstrong A.J. et al. Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2019;17(5):479–505. DOI: 10.6004/jnccn.2019.0023</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Turkbey B., Rosenkrantz A.B., Haider M.A. et al. Prostate Imaging Reporting and Data System Version 2.1: 2019 Update of Prostate Imaging Reporting and Data System Version 2. Eur Urol 2019;76(3):340–51. DOI: 10.1016/j.eururo.2019.02.033</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Corcoran N.M., Hong M.K., Casey R.G. et al. Upgrade in Gleason score between prostate biopsies and pathology following radical prostatectomy significantly impacts upon the risk of biochemical recurrence. BJU Int 2011;108(8 Pt 2):E202–10. DOI: 10.1111/j.1464-410X.2011.10119.x</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>García-Barreras S., Sanchez-Salas R., Mejia-Monasterio C. et al. Biochemical recurrence-free conditional probability after radical prostatectomy: a dynamic prognosis. Int J Urol 2019;26(7):725–30. DOI: 10.1111/iju.13982</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Abbas T.O., Al-Naimi A.R., Yakoob R.A. et al. Prostate cancer metastases to the rectum: a case report. World J Surg Oncol 2011;9:56. DOI: 10.1186/1477-7819-9-56</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Yoo S., Kim J.K., Jeong I.G. Multiparametric magnetic resonance imaging for prostate cancer: a review and update for urologists. Korean J Urol 2015;56(7):487–97. DOI: 10.4111/kju.2015.56.7.487</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Sandgren K., Westerlinck P., Jonsson J.H. et al. Imaging for the detection of locoregional recurrences in biochemical progression after radical prostatectomy – a systematic review. Eur Urol Focus 2019;5(4):550–60. DOI: 10.1016/j.euf.2017.11.001</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Oppenheimer D.C., Weinberg E.P., Hollenberg G.M. et al. Multiparametric magnetic resonance imaging of recurrent prostate cancer. J Clin Imaging Sci 2016;6:18. DOI: 10.4103/2156-7514.181494</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Barrett T., Gill A.B., Kataoka M.Y. et al. DCE and DW MRI in monitoring response to androgen deprivation therapy in patients with prostate cancer: a feasibility study. Magn Reson Med 2012;67(3):778–85. DOI: 10.1002/mrm.23062</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Hotker A.M., Mazaheri Y., Zheng J. et al. Prostate cancer: assessing the effects of androgen-deprivation therapy using quantitative diffusion-weighted and dynamic contrast-enhanced MRI. Eur Radiol 2015;25(9):2665–72. DOI: 10.1007/s00330-015-3688-1</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Jie C., Rongbo L., Ping T. The value of diffusion-weighted imaging in the detection of prostate cancer: a meta-analysis. Eur Radiol 2014;24(8):1929–41. DOI: 10.1007/s00330-014-3201-2</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Mocikova I., Babela J., Balaz V. Prostate cancer – the role of magnetic resonance imaging. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2012;156(2):103–7. DOI: 10.5507/bp.2012.025</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Chen Y.J., Chu W.C., Pu Y.S. et al. Washout gradient in dynamic contrast-enhanced MRI is associated with tumor aggressiveness of prostate cancer. J Magn Reson Imaging 2012;36(4):912–9. DOI: 10.1002/jmri.23723</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Park H., Kim S.H., Kim J.Y. Dynamic contrast-enhanced magnetic resonance imaging for risk stratification in patients with prostate cancer. Quant Imaging Med Surg 2022;12(1):742–51. DOI: 10.21037/qims-21-455</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Cornford P., Bellmunt J., Bolla M. et al. EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part II: treatment of relapsing, metastatic, and castration-resistant prostate cancer. Eur Urol 2017;71(4):630–42. DOI: 10.1016/j.eururo.2016.08.002</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Valle L.F., Lehrer E.J., Markovic D. et al. A systematic review and meta-analysis of local salvage therapies after radiotherapy for prostate cancer (MASTER). Eur Urol 2021;80(3):280–92. DOI: 10.1016/j.eururo.2020.11.010</mixed-citation></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">Solodkiy V.A., Pavlov A.Yu., Tsybulskiy A.D. Salvage high-dose-rate brachytherapy for local prostate cancer recurrence after radical radiotherapy. Onkourologiya = Cancer Urology 2016;12(4):81–6. (In Russ.). DOI: 10.17650/1726-9776-2016-12-4-81-86</mixed-citation><mixed-citation xml:lang="ru">Солодкий В.А., Павлов А.Ю., Цыбульский А.Д. Спасительная брахитерапия высокой мощности дозы при местном рецидиве рака предстательной железы после радикальных радиотерапевтических методов лечения. Онкоурология 2016;12(4):81–6. DOI: 10.17650/1726-9776-2016-12-4-81-86</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><mixed-citation>Spratt D.E., Dess R.T., Zumsteg Z.S. et al. A systematic review and framework for the use of hormone therapy with salvage radiation therapy for recurrent prostate cancer. Eur Urol 2018;73(2):156–65. DOI: 10.1016/j.eururo.2017.06.027</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Schmidt-Hegemann N.S., Zamboglou C., Mason M. et al. ESTRO-ACROP recommendations for evidence-based use of androgen deprivation therapy in combination with external-beam radiotherapy in prostate cancer. Radiother Oncol 2023;183:109544. DOI: 10.1016/j.radonc.2023.109544</mixed-citation></ref></ref-list></back></article>
