Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press170610.17650/1726-9776-2024-20-1-146-152REVIEWSОБЗОРЫOligometastatic prostate cancer: local treatment and metastasis-directed therapyОлигометастатический рак предстательной железы: локальное лечение и метастазнаправленная терапияhttps://orcid.org/0000-0001-7335-895XTer-OvanesovM. D.Тер-ОванесовМ. Д.
Russian Federation

2 Budayskaya St., Moscow 129128; Build. 1, 20 Delegatskaya St., Moscow 127473

129128 Москва, ул. Будайская, 2; 127473 Москва, ул. Делегатская, 20, стр. 1

https://orcid.org/0000-0002-5949-6915YagudaevD. M.ЯгудаевД. М.
Russian Federation

Daniel M. Yagudaev.

2 Budayskaya St., Moscow 129128; 6 Miklukho-Maklaya St., Moscow 117198

Ягудаев Даниэль Меерович - доктор медицинских наук, профессор кафедры эндоскопической урологии и ультразвуковой диагностики ФНМО МИ «РУДН»; заведующий отделением онкоурологии ЧУЗ «ЦКБ «РЖД-Медицина».

129128 Москва, ул. Будайская, 2; 117198 Москва, ул. Миклухо-Маклая, 6

y.d.m.21@mail.ruhttps://orcid.org/0000-0001-8524-129XAnikanovaE. V.АникановаЕ. В.
Russian Federation

2 Budayskaya St., Moscow 129128; Build. 1, 20 Delegatskaya St., Moscow 127473

129128 Москва, ул. Будайская, 2; 127473 Москва, ул. Делегатская, 20, стр. 1

https://orcid.org/0000-0002-6157-0213MedvedevK. I.МедведевК. И.
Russian Federation

Build. 1, 20 Delegatskaya St., Moscow 127473

127473 Москва, ул. Делегатская, 20, стр. 1

Central Clinical Hospital “RZD-Medicine”ЧУЗ «Центральная клиническая больница «РЖД-Медицина»Russian University of Medicine, Ministry of Health of RussiaФГБОУ ВО «Российский университет медицины» Минздрава РоссииPeoples’ Friendship University of Russia named after Patrice LumumbaФГАОУ ВО «Российский университет дружбы народов им. Патриса Лумумбы»180520242011461520907202309042024https://oncourology.abvpress.ru/oncur/article/view/1706

The article is dedicated to the modern methods of diagnosis and treatment of oligometastatic prostate cancer based on a large amount of literature data. The main goal of metastasis-directed therapy in oligometastatic prostate cancer is slowing of metastatic process, increased time to palliative androgen deprivation therapy, and cure of the patient. Currently, there is not enough high-quality data on treatment and effectiveness of metastasis-directed therapy. Terminology standardization, use of the full potential of positron emission tomography/computed tomography imaging with prostate-specific membrane antigen, its combination with molecular and genetic tests, and stratification of risk factors for each individual patient are necessary.

Статья посвящена современным методам диагностики и лечения олигометастатического рака предстательной железы на основании анализа большого количества данных литературы. Основная цель метастазнаправленной терапии при олигометастатическом раке предстательной железы – замедление прогрессирования метастатического процесса, увеличение времени до начала паллиативной андрогендепривационной терапии и излечение пациента. В настоящее время недостаточно высококачественных данных о лечении и эффективности метастазнаправленной терапии. Необходимо стандартизировать терминологию, использовать весь потенциал визуализации позитронно-эмиссионной томографии, совмещенной с компьютерной томографией, с простатическим специфическим мембранным антигеном, комбинировать ее с молекулярно-генетическими исследованиями и стратифицировать факторы риска для каждого пациента в отдельности.

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