Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press15710.17650/1726-9776-2010-6-2-73-77REVIEWОБЗОРHYPERBARIC OXYGENATION IN THE TREATMENT OF LATE POSTRADIATION CYSTITISГИПЕРБАРИЧЕСКАЯ ОКСИГЕНАЦИЯ В ЛЕЧЕНИИ ПОЗДНИХ ПОСТЛУЧЕВЫХ ЦИСТИТОВLoranO. B.ЛоранО. Б.
Russian Federation
ples-doc@mail.ruSinyakovaL. A.СиняковаЛ. А.
Russian Federation
ples-doc@mail.ruMitrokhinA. A.МитрохинА. А.
Russian Federation
ples-doc@mail.ruPlesovskyA. M.ПлесовскийА. М.
Russian Federation
ples-doc@mail.ruDepartment of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, MoscowКафедра урологии и хирургической андрологии ГОУ ДПО РМАПО, Москва300620106273772907201429072014https://oncourology.abvpress.ru/oncur/article/view/157

Radiotherapy (RT) alone or in combination with other treatment modalities is widely used in the treatment of urological and gynecological cancers. Despite the fact that there is continuous technical improvement of equipment and RT procedures, the frequency of complications due to this treatment option remains high in the early and late periods and generally requires complex and long-term care. One of the leading pathogenetic mechanisms responsible for the development of these complications is vascular endothelial damage and hence decreased blood and oxygen supply to the tissues of pelvic organs. Postradiation cystitis is one of the commonest complications of RT. Among various treatment modalities for postradiation hemorrhagic cystitis, hyperbaric oxygenation yielded good results particularly in cases of ineffective standard treatments.

Лучевая терапия (ЛТ) как самостоятельно, так и в комбинации с другими видами терапии широко применяется при лечении онкоурологических и онкогинекологических заболеваний. Несмотря на постоянное техническое совершенствование оборудования и методов проведения ЛТ, частота осложнений такого вида лечения в ранние и отдаленные сроки остается высокой и, как правило, требуется сложное и длительное лечение. Одним из ведущих патогенетических механизмов развития данных осложнений является повреждение эндотелия сосудов и, как следствие, снижение кровоснабжения и оксигенации тканей органов таза. Одним из наиболее частых осложнений радиотерапии является постлучевой цистит. Среди различных методов лечения постлучевого геморрагического цистита гипербарическая оксигенация показала хорошие результаты, особенно в тех случаях, когда стандартные методы лечения оказывались неэффективными.

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