Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press15510.17650/1726-9776-2011-7-2-52-53PROSTATE CANCERРАК ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫPROGNOSTIC FACTORS OF PROSTATE CANCER BEFORE AND AFTER RADICAL PROSTATECTOMYПРОГНОСТИЧЕСКИЕ ФАКТОРЫ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ ДО И ПОСЛЕ РАДИКАЛЬНОЙ ПРОСТАТЭКТОМИИVelievE. I.ВелиевЕ. И.
Russian Federation
splen@bk.ruOkhritsV. E.ОхрицВ. Е.
Russian Federation
splen@bk.ruObeidA. Kh.ОбейдА. Х.
Russian Federation
splen@bk.ruDepartment of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, MoscowКафедра урологии и хирургической андрологии РМАПО, Москва300620117252532907201429072014https://oncourology.abvpress.ru/oncur/article/view/155

Objective: to assess a correlation between the preoperative prognostic characteristics and the pathologic stage and to determine whether a positive surgical margin is present after radical prostatectomy (RPE).

Materials and methods. The materials of 224 patients with prostate cancer (PC) who had undergone RPE at the Clinic of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, were analyzed.

Results. The patients’ median age was 62 (43–78) years. Sixty-seven (29.9 %), 46 (20.5%), and 111 (49.6 %) patients were referred to as low-, moderate-, and high-risk groups, respectively. A positive surgical margin was observed in 11.9, 28.3, and 38.7 % of the patients in the low-, moderate-, and high-risk groups, respectively (р = 0.0003). The predictors of a positive surgical margin were the percent of involved biopsy specimens (R = 0.34) and Gleason score (R = 0.31) and perineural invasion. According to multivariate analysis, neither the preoperative level of prostate-specific antigen, nor the clinical stage showed any correlation with the positive surgical margin and the pathologic stage after RPE.

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