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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1471</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2021-17-3-145-147</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Central renal cell carcinoma: a diagnostic dilemma</article-title><trans-title-group xml:lang="ru"><trans-title>Рак почки при центральной локализации диагностическая дилемма</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Mugialan</surname><given-names>P.</given-names></name><address><country country="MY">Malaysia</country></address><bio><p>Department of Urology, Hospital Pengajar UPM; Department of Urology, Fakulti Perubatan Dan Sains Kesihatan UPM.</p><p>Kuala Lumpur</p></bio><email>drmugialan@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Christopher</surname><given-names>L.K.S.</given-names></name><address><country country="MY">Malaysia</country></address><bio><p>Department of Urology, Fakulti Perubatan Dan Sains Kesihatan UPM; Department of Surgery, Hospital Pengajar UPM.</p><p>Kuala Lumpur</p></bio><email>chriskslee@upm.edu.my</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khairul Asri</surname><given-names>M. G.</given-names></name><name xml:lang="ru"><surname>Khairul Asri</surname><given-names>M.G.</given-names></name></name-alternatives><address><country country="MY">Malaysia</country></address><bio><p>Department of Urology, Fakulti Perubatan Dan Sains Kesihatan UPM; Department of Surgery, Hospital Pengajar UPM.</p><p>Kuala Lumpur</p></bio><email>mfairuz.ms@upm.edu.my</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Jagwani</surname><given-names>A.</given-names></name><name xml:lang="ru"><surname>Jagwani</surname><given-names>А.</given-names></name></name-alternatives><address><country country="MY">Malaysia</country></address><bio><p>Arvind Vashdev Jagwani - Department of Urology, Fakulti Perubatan Dan Sains Kesihatan UPM; Department of Surgery, Hospital Pengajar UPM.</p><p>Kuala Lumpur</p></bio><email>jagwani2899@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff id="aff1"><institution>Hospital Pengajar University Putra Malaysia</institution></aff><aff id="aff2"><institution>UPM</institution></aff><pub-date date-type="pub" iso-8601-date="2021-11-11" publication-format="electronic"><day>11</day><month>11</month><year>2021</year></pub-date><volume>17</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>145</fpage><lpage>147</lpage><history><date date-type="received" iso-8601-date="2021-07-30"><day>30</day><month>07</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-09-17"><day>17</day><month>09</month><year>2021</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1471">https://oncourology.abvpress.ru/oncur/article/view/1471</self-uri><abstract xml:lang="en"><p>Centrally Located renal tumor poses a diagnostic challenge to differentiate between renal cell carcinoma and transitional cell carcinoma. Imaging alone is not sufficient to make the diagnosis, some invasive diagnostic investigations are required to ascertain the diagnosis. We present a 60 years old gentleman, who presented dyspepsia and further investigation by contrasted CT kidney revealed a centrally located right renal tumor. Before making a management decision, we performed the right renal biopsy of the tumor which turns out to be a renal cell carcinoma. Henceforth, we performed a robotic-assisted laparoscopic right nephrectomy. A renal biopsy, in this case, assisted to decide only radical nephrectomy instead of radical nephroureterectomy which has higher associated morbidity. Thus, it is important to make confirm by tissue biopsy before deciding on surgery in case of the central renal tumor as this prevents subjecting a patient to under-or overtreatment.</p></abstract><trans-abstract xml:lang="ru"><p>Опухоль почки с центральной локализацией представляет собой проблему для дифференциальной диагностики почечно-клеточной карциномы и переходно-клеточного (уротелиального) рака. Применения только методов визуализации недостаточно для постановки диагноза, требуются определенные инвазивные диагностические исследования. В статье описан пациент, 60 лет, с диспепсией. При обследовании по данным компьютерной томографии почек с контрастированием была выявлена опухоль правой почки с центральной локализацией. Перед принятием решения о лечении была выполнена биопсия опухоли почки, по результатам которой диагностирована почечноклеточная карцинома. Пациенту выполнили операцию - робот-ассистированную лапароскопическую нефрэктомию справа. В данном клиническом случае биопсия почки помогла принять решение в пользу радикальной нефрэктомии вместо радикальной нефруретерэктомии, последняя ассоциирована с большей частотой послеоперационных осложнений. Таким образом, в случае опухоли почки с центральной локализацией важно выполнять биопсию ткани перед принятием решения о хирургическом вмешательстве, так как это предотвращает неполное (undertreament) или излишнее (overtreatment) лечение пациента.</p></trans-abstract><kwd-group xml:lang="en"><kwd>central renal cell carcinoma</kwd><kwd>renal pelvis urothelial carcinoma</kwd><kwd>upper tract urothelial carcinoma</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>почечно-клеточный рак с центральной локализацией</kwd><kwd>уротелиальный рак лоханки</kwd><kwd>уротелиальный рак верхних мочевых путей</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">NATIONAL CANCER REGISTRY 2012-2016, pg. 26</mixed-citation><mixed-citation xml:lang="ru">National Cancer Registry 2012-2016. 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