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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1409</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2021-17-2-157-167</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The role of targeted biopsy methods in the prostate cancer diagnosis</article-title><trans-title-group xml:lang="ru"><trans-title>Роль прицельных методов биопсии в диагностике рака предстательной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1795-1913</contrib-id><name-alternatives><name xml:lang="en"><surname>Petov</surname><given-names>V. S.</given-names></name><name xml:lang="ru"><surname>Петов</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Vladislav Sergeevich Petov.</p><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>Петов Владислав Сергеевич - аспирант.</p><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p><p>SPIN-код: 5153-9884</p></bio><email>pettow@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3580-5111</contrib-id><name-alternatives><name xml:lang="en"><surname>Sapelko</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Сапелко</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Danilov</surname><given-names>S. P.</given-names></name><name xml:lang="ru"><surname>Данилов</surname><given-names>С. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chernov</surname><given-names>Ya. N.</given-names></name><name xml:lang="ru"><surname>Чернов</surname><given-names>Я. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4369-173X</contrib-id><name-alternatives><name xml:lang="en"><surname>Taratkin</surname><given-names>M. S.</given-names></name><name xml:lang="ru"><surname>Тараткин</surname><given-names>М. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Amosov</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Амосов</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7169-2209</contrib-id><name-alternatives><name xml:lang="en"><surname>Enikeev</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Еникеев</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2571-8671</contrib-id><name-alternatives><name xml:lang="en"><surname>Krupinov</surname><given-names>G. E.</given-names></name><name xml:lang="ru"><surname>Крупинов</surname><given-names>Г. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 1, 2 Bol'shaya Pirogovskaya St., Moscow 119435.</p></bio><bio xml:lang="ru"><p>119435 Москва, ул. Большая Пироговская, 2, стр. 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute of Urology and Human Reproductive Health, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Институт урологии и репродуктивного здоровья человека, Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет) Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-07-25" publication-format="electronic"><day>25</day><month>07</month><year>2021</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>157</fpage><lpage>167</lpage><history><date date-type="received" iso-8601-date="2021-02-09"><day>09</day><month>02</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-29"><day>29</day><month>04</month><year>2021</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1409">https://oncourology.abvpress.ru/oncur/article/view/1409</self-uri><abstract xml:lang="en"><p>The current prostate cancer screening program results in unnecessary biopsies in a quarter of patients, overdiagnosis of clinically insignificant prostate cancer (ISUP 1) and overtreatment. Intoducing multiparametric magnetic resonance imaging into routine practice before biopsy allows to decrease the number of biopsies, thereby reducing the burden on clinicians and increasing the likelihood of detecting clinically significant forms of prostate cancer (ISUP &gt;2).  The objective of this literature review is to compare targeted biopsy techniques and to determine their current role in the prostate cancer diagnosis.</p></abstract><trans-abstract xml:lang="ru"><p>    </p><p>Современная программа скрининга рака предстательной железы приводит к выполнению ненужных биопсий у четверти пациентов, гипердиагностике клинически незначимого рака предстательной железы (ISUP 1) и избыточному лечению. Активное внедрение мультипараметрической магнитно-резонансной томографии в повседневную практику перед проведением биопсии позволяет (без ущерба для диагностики) уменьшать количество выполняемых биопсий, тем самым снижать нагрузку на врачей и повышать вероятность выявления клинически значимых форм рака предстательной железы (ISUP ≥2).  Цель обзора - сравнение методов прицельной биопсии и определение их текущей роли в диагностике рака предстательной железы.</p><p> </p></trans-abstract><kwd-group xml:lang="en"><kwd>prostate cancer</kwd><kwd>multiparametric magnetic resonance imaging</kwd><kwd>targeted biopsy</kwd><kwd>prostate biopsy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак предстательной железы</kwd><kwd>мультипараметрическая магнитно-резонансная томография</kwd><kwd>прицельная биопсия</kwd><kwd>биопсия предстательной железы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">State of oncological care in Russia in 2019. 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