Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press14010.17650/1726-9776-2013-9-4-25-36PROSTATE CANCERРАК ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫROLE OF MULTIPARAMETRIC MRI IN THE DETECTION AND LOCALIZATION OF EARLY-STAGE PROSTATE CANCERРОЛЬ МУЛЬТИПАРАМЕТРИЧЕСКОЙ МРТ В ВЫЯВЛЕНИИ И ЛОКАЛИЗАЦИИ РАННЕГО РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫAkhverdievaG. I.АхвердиеваГ. И.
Russian Federation

Department of Radiodiagnosis, Radiotherapy, and Medical Physics

кафедра лучевой диагностики, лучевой терапии и медицинской физики

doctor_gulya@mail.ruSanaiE. B.СанайЭ. Б.
Russian Federation
doctor_gulya@mail.ruPanovV. O.ПановВ. О.
Russian Federation

Department of Radiodiagnosis, Radiotherapy, and Medical Physics

кафедра лучевой диагностики, лучевой терапии и медицинской физики

doctor_gulya@mail.ruTyurinI. E.ТюринИ. Е.
Russian Federation

Department of Radiodiagnosis, Radiotherapy, and Medical Physics

кафедра лучевой диагностики, лучевой терапии и медицинской физики

doctor_gulya@mail.ruGubskyI. L.ГубскийИ. Л.
Russian Federation

Department of Radiodiagnosis, Radiotherapy, and Medical Physics

кафедра лучевой диагностики, лучевой терапии и медицинской физики

doctor_gulya@mail.ruKamolovB. Sh.КамоловБ. Ш.
Russian Federation
doctor_gulya@mail.ruKhachaturyanA. V.ХачатурянА. В.
Russian Federation
doctor_gulya@mail.ruResearch Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowНИИ клинической онкологии ФГБУ «РОНЦ им. Н. Н. Блохина» РАМНRussian Medical Academy of Postgraduate Education, MoscowРМАПОN.I. Pirogov Russian National Research Medical University, MoscowРНИМУ им. Н. И. Пирогова, Москва301220139425362807201428072014https://oncourology.abvpress.ru/oncur/article/view/140

The efficiency of prostate cancer (PC) diagnosis using multipatametric magnetic resonance imaging (MRI) was evaluated. Unlike most of investigations of the similar problem, this trial provides an objective assessment applying the method of statistical analysis - binary logistic regression. It used data on 166 patients, including primary patients (with suspected PC), as well as patients with the established diagnosis of PC, those with a history of negative biopsy, and those with suspected recurrent PC. Some patients underwent target biopsy, the results of which were then employed for statistical processing. The data of the analysis showed that the sensitivity, specificity, and total accuracy of the method using the created model of binary logistic regression at the separation value of 0.625 were 75.0, 85.2, and 79.7%, respectively. The efficiency of diffusion-weighted images (DWI) with varying weighing degree by water molecule diffusion (b factor) on MRI systems with different magnetic field strength (1.5 and 3 Tesla) was also evaluated. There were no statistically significant differences in normalized absolute signal intensity as to the contralateral gland portion) in DWI with b factors of 1000 and 2000 between the MRI systems with a magnetic field strength of 1.5 and 3.0 Tesla.

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