Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press119610.17650/1726-9776-2005-1-3-21-26DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORSДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫNephroblastoma in adultsНефробластома у взрослыхMatveyevV. B.МатвеевВ. Б.
Russian Federation
RoshchinD. A.РощинД. А.
Russian Federation
VolkovaM. I.ВолковаМ. И.
Russian Federation
ГУ РОНЦ им. Н.Н. Блохина РАМН300920051321261902202019022020https://oncourology.abvpress.ru/oncur/article/view/1196

Nephroblastoma (NB), a childhood embryonic tumor, accounts for less than 1% of all neoplasms in adults. The algorithm of an examination of patients aged above 14 years who has suspected NB should include angiography in addition to ultrasound computed tomography and computed tomography. Verification of its diagnosis in adults before therapy requires fine-needle tumor biopsy. Treatment for NB in adults should be multimodality and include neoadjuvant chemotherapy, primary tumor removal, and subsequent chemoradiation therapy. The prognosis is fair in patients over 14 years of age who had a localized NB and poor in those with locally extended and disseminated tumors. It is necessary to perform multicenter studies in order to develop an optimal therapeutic algorithm and to improve the results of treatment for NB in adults.

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1. Шароев Т.А., Бойченко Е.И. Нефробластома у детей //Энциклопедия клинической онкологии: Руководство для практикующих врачей / Под ред. М.И. Давыдова. — М., 2004. — С. 76 — 767.Шароев Т.А., Бойченко Е.И. Нефробластома у детей //Энциклопедия клинической онкологии: Руководство для практикующих врачей / Под ред. М.И. Давыдова. — М., 2004. — С. 76 — 767.2. Butler D., Buchino J.J., Jose B. et al. Wilms’ tumor in an adult: a case report and review of the literature //J.Ky.Med.Assoc. — 1997. — Vol. 95. — P. 191—196.Butler D., Buchino J.J., Jose B. et al. Wilms’ tumor in an adult: a case report and review of the literature //J.Ky.Med.Assoc. — 1997. — Vol. 95. — P. 191—196.3. Carmona Campos E., Zarate Rodriguez E. Wilms tumor in adults. Report of a case //Actas.Urol.Esp. — 2001. — Vol. 25. — №10 — P. 755—758.Carmona Campos E., Zarate Rodriguez E. Wilms tumor in adults. Report of a case //Actas.Urol.Esp. — 2001. — Vol. 25. — №10 — P. 755—758.4. Kumar R., Ampara E., David R. et al. Adult Wilms tumor: clinical and radiological features // Urol. Radiol. — 1984. — Vol. 314. — P. 164-169.Kumar R., Ampara E., David R. et al. Adult Wilms tumor: clinical and radiological features // Urol. Radiol. — 1984. — Vol. 314. — P. 164-169.5. Мартин И. Резник, Эндрю К. Новик. Секреты урологии. «Бином». — M., 1997. — С. 70.Мартин И. Резник, Эндрю К. Новик. Секреты урологии. «Бином». — M., 1997. — С. 70.6. Heyns C.F., Rossouw D.J. Spontaneous rupture of adult Wilms’ tumor //Cancer. — 1989. — Vol. 64. — P. 173—177.Heyns C.F., Rossouw D.J. Spontaneous rupture of adult Wilms’ tumor //Cancer. — 1989. — Vol. 64. — P. 173—177.7. Saitoh H., Shiramizu T., Nakamura K., Satoh T. Influence of age and nephrectomy on metastatic patterns in Wilms’ tumors //Tokai. J. Exp. Clin. Med. — 1982. — Vol. 7. — P. 345—354.Saitoh H., Shiramizu T., Nakamura K., Satoh T. Influence of age and nephrectomy on metastatic patterns in Wilms’ tumors //Tokai. J. Exp. Clin. Med. — 1982. — Vol. 7. — P. 345—354.8. Abe Kazuhiro, Wada Tetsuro, Ueda Masataka et al. Wilms tumor in adult.//Acta.Urol.Jap. — 2000. — Vol. 46, № 6. — P. 405 — 408.Abe Kazuhiro, Wada Tetsuro, Ueda Masataka et al. Wilms tumor in adult.//Acta.Urol.Jap. — 2000. — Vol. 46, № 6. — P. 405 — 408.9. Мавричев А.С., Красный С.А., Поляков С.Л. и др. Опухоли почек у детей // Онкоурология. — Минск, 2001. — С. 93.Мавричев А.С., Красный С.А., Поляков С.Л. и др. Опухоли почек у детей // Онкоурология. — Минск, 2001. — С. 93.10. Hentrich M.U., Meister P., Brack N.G. et al. Adult Wilms’ tumor. Report of two cases and review of the literature // Cancer. — 1995. — Vol. 75. — P. 545—551.Hentrich M.U., Meister P., Brack N.G. et al. Adult Wilms’ tumor. Report of two cases and review of the literature // Cancer. — 1995. — Vol. 75. — P. 545—551.11. Grundy R.G., Hutton C., Middleton H. Outcome of patients with stage III or inoperable WT treated on the second United Kingdom WT protocol (UKWT2); a United Kingdom Children’s Cancer Study Group (UKCCSG) study //Pediatr Blood Cancer. — 2004. — Vol. 42. — P. 311—319.Grundy R.G., Hutton C., Middleton H. Outcome of patients with stage III or inoperable WT treated on the second United Kingdom WT protocol (UKWT2); a United Kingdom Children’s Cancer Study Group (UKCCSG) study //Pediatr Blood Cancer. — 2004. — Vol. 42. — P. 311—319.12. Stefanowicz J., Sierota D., Polczynska K. Stage IV Wilms’ tumour — analysis of treatment results, according to the SIOP 93-01 protocol, at the Medical University of Gdansk //Med Wieku Rozwoj. — 2004. — Vol. 8. — P. 197—200.Stefanowicz J., Sierota D., Polczynska K. Stage IV Wilms’ tumour — analysis of treatment results, according to the SIOP 93-01 protocol, at the Medical University of Gdansk //Med Wieku Rozwoj. — 2004. — Vol. 8. — P. 197—200.13. Babaian R.J., Skinner D.G., Waisman J. Wilms’ tumor in the adult patient: diagnosis, management, and review of the world medical literature //Cancer. — 1980. — Vol. 45. — P. 1713—1719.Babaian R.J., Skinner D.G., Waisman J. Wilms’ tumor in the adult patient: diagnosis, management, and review of the world medical literature //Cancer. — 1980. — Vol. 45. — P. 1713—1719.14. Nishimura M., Takenawa J., Okada K. et al. Adult Wilms tumor: a case of prolonged survival achieved by multimodal treatment //Hinyokika. Kiyo. — 1987. — Vol. 33. — P. 1226—1231.Nishimura M., Takenawa J., Okada K. et al. Adult Wilms tumor: a case of prolonged survival achieved by multimodal treatment //Hinyokika. Kiyo. — 1987. — Vol. 33. — P. 1226—1231.15. Terenziani M., Spreafico F., Collini P. et al. Adult Wilms’ tumor: A monoinstitutional experience and a review of the literature //Cancer. — 2004. — Vol. 15. — P. 289—293.Terenziani M., Spreafico F., Collini P. et al. Adult Wilms’ tumor: A monoinstitutional experience and a review of the literature //Cancer. — 2004. — Vol. 15. — P. 289—293.16. Wu H.Y., Snyder H.M., D’angio G.J. Wilms’ tumor management.// Curr. Opin. Urol. — 2005. — Vol. 15. — P. 273—276.Wu H.Y., Snyder H.M., D’angio G.J. Wilms’ tumor management.// Curr. Opin. Urol. — 2005. — Vol. 15. — P. 273—276.17. Baba K., Yamaguchi O., Nomiya M. et al. A case of adult Wilms’ tumor with vena caval involvement //Hinyokika. Kiyo. — 1995. — Vol. 41. — P. 369 — 372.Baba K., Yamaguchi O., Nomiya M. et al. A case of adult Wilms’ tumor with vena caval involvement //Hinyokika. Kiyo. — 1995. — Vol. 41. — P. 369 — 372.18. Zhao Y.B., Zheng S.B., Mao X.M. et al. Clinical effects of preoperative chemotherapy for Wilms tumor// Di Yi Jun Yi Da Xue Xue Bao. — 2004. — Vol. 24. — P. 722—724.Zhao Y.B., Zheng S.B., Mao X.M. et al. Clinical effects of preoperative chemotherapy for Wilms tumor// Di Yi Jun Yi Da Xue Xue Bao. — 2004. — Vol. 24. — P. 722—724.19. Buchino J.J., Jose B. et al. Wilms’ tumor in an adult: a case report and review of the literature //J.Ky.Med.Assoc. — 1997. — Vol. 95. — P. 191—196.Buchino J.J., Jose B. et al. Wilms’ tumor in an adult: a case report and review of the literature //J.Ky.Med.Assoc. — 1997. — Vol. 95. — P. 191—196.20. Orditura M., De Vita F., Catalano G. Adult Wilms’ tumor: a case report//Cancer. — 1997. — Vol. 80. — P. 1961—1965.Orditura M., De Vita F., Catalano G. Adult Wilms’ tumor: a case report//Cancer. — 1997. — Vol. 80. — P. 1961—1965.21. Reinhard H., Aliani S., Ruebe C. et al. Wilms’ tumor in adults: results of the Society of Pediatric Oncology (SIOP) 93-01. Society for Pediatric Oncology and Hematology (GPOH) Study //J. Clin. Oncol. — 2004. — Vol. 15, № 22. — P. 4500—4506.Reinhard H., Aliani S., Ruebe C. et al. Wilms’ tumor in adults: results of the Society of Pediatric Oncology (SIOP) 93-01. Society for Pediatric Oncology and Hematology (GPOH) Study //J. Clin. Oncol. — 2004. — Vol. 15, № 22. — P. 4500—4506.