Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press116210.17650/1726-9776-2006-2-3-14-18DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. RENAL CANCERДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак почкиCytogenetic studies of bilateral renal cell carcinomaЦитогенетические исследования при двустороннем раке почекMatveyevV. B.МатвеевВ. Б.
Russian Federation

Отделение урологии

MarilovT. V.МариловТ. В.
Russian Federation

Отделение урологии

JunkerK.ЮнкерК.
Germany
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical SciencesРОНЦ им. Н.Н. Блохина РАМНJena University Urology ClinicУрологическая клиника Йенского университета300920062314181802202018022020https://oncourology.abvpress.ru/oncur/article/view/1162

Aim. To study chromosomal abnormalities in bilateral renal cell carcinoma (RCC).

Materials and methods. Paraffin-embedded specimens from 8 patients with bilateral RCC were examined by comparative genomic hybridization.

Results. 1 to 6 chromosomal aberrations were found in each sample. The same chromosomal aberrations in both tumors in 7 (87.5%) cases chromosomal changes were different in one (12.5%) case.

Conclusion. Further genetic studies of bilateral RCC may give a better insight into the biology, diagnosis, and treatment of bilateral RCC.

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