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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1152</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2006-2-4-46-49</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. PROSTATE CANCER</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак предстательной железы</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Primary hormonal resistance of prostate cancer: clinical and morphological aspects</article-title><trans-title-group xml:lang="ru"><trans-title>Клинико-морфологические аспекты изначально первичной гормональной резистентности рака предстательной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Karpov</surname><given-names>P. F.</given-names></name><name xml:lang="ru"><surname>Карпов</surname><given-names>П. Ф.</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belenky</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Беленький</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Municipal Multidisciplinary Clinical Hospital Four, Dnepropetrovsk</institution></aff><aff><institution xml:lang="ru">Городская многопрофильная клиническая больница №4, Днепропетровск</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2006-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2006</year></pub-date><volume>2</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>46</fpage><lpage>49</lpage><history><date date-type="received" iso-8601-date="2020-02-17"><day>17</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-17"><day>17</day><month>02</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1152">https://oncourology.abvpress.ru/oncur/article/view/1152</self-uri><abstract xml:lang="en"><p>By using the routine studies, the authors have analyzed clinical and morphological data of 129 prostate cancer (PC) patients, 48-92 years old with different clinical stages. PC turned out to be initially heterogenic in the composition of tumor cells (cytotypic and immunophenotypic heterogenicity). Therefore combined PC treatment should take into account the presence of hormone-resistant tumor cells even when a neoplasm looks at the light microscopy as a usual low- or moderate-grade adenocarcinoma with a great number of adrenoceptors in the tumor cells.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Сивков А.В., Алфимов А.Е., Имамов О.Э. Гормонально-резистентный рак предстательной железы: современные методы медикаментозной профилактики и лечения. Урология1999;(5):33–9.</mixed-citation><mixed-citation xml:lang="ru">Сивков А.В., Алфимов А.Е., Имамов О.Э. Гормонально-резистентный рак предстательной железы: современные методы медикаментозной профилактики и лечения. 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