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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1111</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2007-3-3-5-9</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Malignant urinary tract tumors in polyneoplasias</article-title><trans-title-group xml:lang="ru"><trans-title>Злокачественные опухоли мочеполовой системы при первично-множественных опухолях</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Segedin</surname><given-names>R. Ye.</given-names></name><name xml:lang="ru"><surname>Сегедин</surname><given-names>Р. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zerkalov</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Зеркалов</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shaplygin</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Шаплыгин</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Furashov</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Фурашов</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Burdenko Main Military Clinical Hospital</institution></aff><aff><institution xml:lang="ru">Главный военный клинический госпиталь им. Н.Н. Бурденко</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2007-09-30" publication-format="electronic"><day>30</day><month>09</month><year>2007</year></pub-date><volume>3</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>5</fpage><lpage>9</lpage><history><date date-type="received" iso-8601-date="2020-02-15"><day>15</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-15"><day>15</day><month>02</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1111">https://oncourology.abvpress.ru/oncur/article/view/1111</self-uri><abstract xml:lang="en"><p><bold>Introduction.</bold> Primary multiple tumors (polyneoplasia) represent synchronous or consecutive and independent from each other development of two or more tumors. Frequency of urinary tract tumors composing primary multiple tumors is from 10 to 13,5%. There is a constant growing interest in primary multiple tumors due to the increase of patients with this kind of disease. Up to the present, many issues related to diagnostics and method choice to treat primary multiple tumors remain questionable.</p><p><bold>Materials and methods.</bold> In our research, 1632 patients with urinary tract tumors were treated in the N.N. Burdenko Main Military Hospital's Oncourology Department from December 1998 to December 2005. Out of them, 570 (34,9%) were patients with prostate cancer, 469 (28,8%) with bladder cancer, 442 (27,1%) patients with kidney tumors, and 78 (4,8%) with renal pelvis tumor. Out of all patients included in our research, 89 (5,6%) patients were with primary multiple tumors. In average, these patients were 69 years old. Out of them, 8 patients had tumors of three organs.</p><p><bold>Results.</bold> Nephrectomy (366) and/or kidney resection (114) were performed to patients with kidney tumors. Bladder transurethral resection, bladder resection, and cystectomy with various methods of urine derivation (118) (bilateral ureterocutaneostomia (86), Shtuder's plastic surgery of artificial bladder - 22, Bricker's formation of a urinary duct - 8, and 2 bladder plastic surgery with a skin-muscle graft) were performed to patients with bladder cancer. Prostatectomy (109), or hormonal therapy and radiotherapy were performed to patients with prostate cancer. 42% of patients were diagnosed with urinary system cancer as a part of primary multiple tumors in the first stage, 28% in the second, 18% in the third, and 12% in the forth. The group of patients with kidney tumor 42 (54%) had the largest amount of primary multiple tumors due to cancer of both kidneys 26 (33,8%). In one case, the second tumor was diagnosed 13 years after the first tumor had been diagnosed. During the first month after the first tumor had been diagnosed 42,7% (42), the second one was diagnosed. In a period from 3 to 6 months, the second tumor was diagnosed in 18,2% (16) cases. In cases when cancer was diagnosed for the first time, there were 45% (40) tumors of the first stage, 16% (15) of the second stage, 14,5% (12) of the third, and 24,5% (21) of the forth.</p><p><bold>Conclusion.</bold> Urinary tract tumors composing primary multiple tumors are not rare, and their diagnosis mainly is incidental. Results of treatment depend not only on the spread of tumor process but also on timely and appropriate combined treatment. Surgery treatment of synchronically diagnosed tumors has to be performed with one surgery, and not to be divided into several operations, because with this method, time factor is very important.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Первично-множественные злокачественные опухоли. Руководство для врачей. Под ред. В.И. Чиссова, А.X. Трахтенберга.</mixed-citation><mixed-citation xml:lang="ru">Первично-множественные злокачественные опухоли. Руководство для врачей. Под ред. В.И. Чиссова, А.X. Трахтенберга.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Попова Т.Н. Лечение первично-множественных синхронных злокачественных новообразований. Вопр онкол 2003;49(3):363—6.</mixed-citation><mixed-citation xml:lang="ru">Попова Т.Н. 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