<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1108</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2008-4-2-73-77</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Drug prophylaxis of the prostate cancer. Long term results analysis</article-title><trans-title-group xml:lang="ru"><trans-title>Медикаментозная профилактика рака предстательной железы. Исследование PCPT. Анализ отдаленных результатов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pushkar</surname><given-names>D. U.</given-names></name><name xml:lang="ru"><surname>Пушкарь</surname><given-names>Д. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rasner</surname><given-names>P. I.</given-names></name><name xml:lang="ru"><surname>Раснер</surname><given-names>П. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Кафедра урологии МГМСУ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2008-06-30" publication-format="electronic"><day>30</day><month>06</month><year>2008</year></pub-date><volume>4</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>73</fpage><lpage>77</lpage><history><date date-type="received" iso-8601-date="2020-02-15"><day>15</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-15"><day>15</day><month>02</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1108">https://oncourology.abvpress.ru/oncur/article/view/1108</self-uri><abstract xml:lang="en"><p>.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Klein E.A., Thompson I.M., Klein E.A. et al. Update on chemoprevention of prostate cancer. Curr Opin Urol 2004;14:143—9.</mixed-citation><mixed-citation xml:lang="ru">Klein E.A., Thompson I.M., Klein E.A. et al. Update on chemoprevention of prostate cancer. Curr Opin Urol 2004;14:143—9.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Isaacs J.T. Control of cell proliferation and cell death in the normal and neoplastic prostate: a stem cell model. In: C.H. Rodgers, D.S. Coffy, G.R. Cunha et al. (eds) Benign prostatic hyperplasia II. NIH Publ. No 87—2881, US dept. Health, Human Serv. Bethesda: NIH; 1987. p. 85—94.</mixed-citation><mixed-citation xml:lang="ru">Isaacs J.T. Control of cell proliferation and cell death in the normal and neoplastic prostate: a stem cell model. In: C.H. Rodgers, D.S. Coffy, G.R. Cunha et al. (eds) Benign prostatic hyperplasia II. NIH Publ. No 87—2881, US dept. Health, Human Serv. Bethesda: NIH; 1987. p. 85—94.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Cabot A. The question of castration for enlarged prostate. Ann Serg 1896;24:256.</mixed-citation><mixed-citation xml:lang="ru">Cabot A. The question of castration for enlarged prostate. Ann Serg 1896;24:256.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Huggins C., Hodges C.V. Studies of prostate cancer: I. The effect of castration on advanced carcinoma of the prostate gland. Arh Surg 1941;43:209.</mixed-citation><mixed-citation xml:lang="ru">Huggins C., Hodges C.V. Studies of prostate cancer: I. The effect of castration on advanced carcinoma of the prostate gland. Arh Surg 1941;43:209.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Сивков А.В., Ощепков В.Н. Фармакотерапия доброкачественной гиперплазии и рака предстательной железы. Финастерид: 20 лет клинической практики лечения больных аденомой предстательной железы. Consilium Medicum 2006;08(4):36–9.</mixed-citation><mixed-citation xml:lang="ru">Сивков А.В., Ощепков В.Н. Фармакотерапия доброкачественной гиперплазии и рака предстательной железы. Финастерид: 20 лет клинической практики лечения больных аденомой предстательной железы. Consilium Medicum 2006;08(4):36–9.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Gormely G.J., Brawley O., Thompson I. The potential application of finasteride for chemoprevention of prostate cancer. Ann N Y Acad Sci 1995;768:163.</mixed-citation><mixed-citation xml:lang="ru">Gormely G.J., Brawley O., Thompson I. The potential application of finasteride for chemoprevention of prostate cancer. Ann N Y Acad Sci 1995;768:163.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Thompson I.M., Goodman P.J., Tangen C.M. et al. The influence of finasteride on the development of prostate cancer. N Engl J Med 2003;349(3):215—24.</mixed-citation><mixed-citation xml:lang="ru">Thompson I.M., Goodman P.J., Tangen C.M. et al. The influence of finasteride on the development of prostate cancer. N Engl J Med 2003;349(3):215—24.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Gormley G.J., Stoner E., Bruskewitz R.C. et al. The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. N Engl J Med 1992;327(17):1185—91.</mixed-citation><mixed-citation xml:lang="ru">Gormley G.J., Stoner E., Bruskewitz R.C. et al. The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. N Engl J Med 1992;327(17):1185—91.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Etzioni R.D., Howlader N., Shaw P.A. et al. Long-term effects of finasteride on prostate specific antigen levels: results from the prostate cancer prevention trial. J Urol 2005;174(3):877—81.</mixed-citation><mixed-citation xml:lang="ru">Etzioni R.D., Howlader N., Shaw P.A. et al. Long-term effects of finasteride on prostate specific antigen levels: results from the prostate cancer prevention trial. J Urol 2005;174(3):877—81.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Thompson I.M., Tangen C.M., Goodman P.J. et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005;294:2996—3002.</mixed-citation><mixed-citation xml:lang="ru">Thompson I.M., Tangen C.M., Goodman P.J. et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005;294:2996—3002.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Thompson I.M., Pauler D.K., Goodman P.J. et al. Prevalence of prostate cancer among men with a prostate-specific antigen level &lt; or = 4,0 ng per milliliter. N Engl J Med 2004;350:2239—46.</mixed-citation><mixed-citation xml:lang="ru">Thompson I.M., Pauler D.K., Goodman P.J. et al. Prevalence of prostate cancer among men with a prostate-specific antigen level &lt; or = 4,0 ng per milliliter. N Engl J Med 2004;350:2239—46.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Carver B.S., Kattan M.W., Scardino P.T. et al. Gleason grade remains an important prognostic predictor in men diagnosed with prostate cancer while on finasteride therapy. BJU Int 2005;95:509—12.</mixed-citation><mixed-citation xml:lang="ru">Carver B.S., Kattan M.W., Scardino P.T. et al. Gleason grade remains an important prognostic predictor in men diagnosed with prostate cancer while on finasteride therapy. BJU Int 2005;95:509—12.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Civantos F. et al. Finasteride effect on prostatic hyperplasia and prostate cancer. J Urol Pathol 1997;6:1—13.</mixed-citation><mixed-citation xml:lang="ru">Civantos F. et al. Finasteride effect on prostatic hyperplasia and prostate cancer. J Urol Pathol 1997;6:1—13.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Bostwick D.G. et al. Treatment changes in prostatic hyperplasia and cancer, including androgen deprivation therapy and radiotherapy. Urol Clin North Am 1999;26:465—79.</mixed-citation><mixed-citation xml:lang="ru">Bostwick D.G. et al. Treatment changes in prostatic hyperplasia and cancer, including androgen deprivation therapy and radiotherapy. Urol Clin North Am 1999;26:465—79.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Yang X.J. et al. Does long-term finasteride therapy affect the histologic features of benign prostate tissue and prostate cancer on needle biopsy? PLESS Study Group. Proscar longterm efficacy and safety study. Urology 1998;53:696—700.</mixed-citation><mixed-citation xml:lang="ru">Yang X.J. et al. Does long-term finasteride therapy affect the histologic features of benign prostate tissue and prostate cancer on needle biopsy? PLESS Study Group. Proscar longterm efficacy and safety study. Urology 1998;53:696—700.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Rubin M.A., Allory Y., Molinie V. et al. Effects of long-term finasteride treatment on prostate cancer morphology and clinical outcome. Urology 2005;66:930—4.</mixed-citation><mixed-citation xml:lang="ru">Rubin M.A., Allory Y., Molinie V. et al. Effects of long-term finasteride treatment on prostate cancer morphology and clinical outcome. Urology 2005;66:930—4.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Bautista O.M. et al. Study desine of the medical Therapy of Prostatic Symptoms (MTOPS) trial. Control Clin Trials 2003;24:224.</mixed-citation><mixed-citation xml:lang="ru">Bautista O.M. et al. Study desine of the medical Therapy of Prostatic Symptoms (MTOPS) trial. Control Clin Trials 2003;24:224.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18. Andriole G.L., Roehborn C., Schulman C. et al. Effect of dutasteride on the detection of prostate cancer in men with benign prostatic hyperplasia. Urology 2004;64:537.</mixed-citation><mixed-citation xml:lang="ru">Andriole G.L., Roehborn C., Schulman C. et al. Effect of dutasteride on the detection of prostate cancer in men with benign prostatic hyperplasia. Urology 2004;64:537.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19. Ishikawa S., Soloway M.S., van der Zwaag R. et al. Prognostic factors in survival free of progression after androgen deprivation therapy for treatment of prostate cancer. J Urol 1989;141(5):1139—42.</mixed-citation><mixed-citation xml:lang="ru">Ishikawa S., Soloway M.S., van der Zwaag R. et al. Prognostic factors in survival free of progression after androgen deprivation therapy for treatment of prostate cancer. J Urol 1989;141(5):1139—42.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20. Raivio T., Santti H., Schatzl G. et al. Reduced circulating androgen bioactivity in patients with prostate cancer. Prostate 2003;55(3):194—8.</mixed-citation><mixed-citation xml:lang="ru">Raivio T., Santti H., Schatzl G. et al. Reduced circulating androgen bioactivity in patients with prostate cancer. Prostate 2003;55(3):194—8.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21. Thompson I.M., Klein E.A., Lippman S.M. et al. Prevention of prostate cancer with finasteride: US/European perspective. Eur Urol 2003;44(6):650—5.</mixed-citation><mixed-citation xml:lang="ru">Thompson I.M., Klein E.A., Lippman S.M. et al. Prevention of prostate cancer with finasteride: US/European perspective. Eur Urol 2003;44(6):650—5.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">22. Marberger M., Adolfsson J., Borkowski A. et al. The clinical implications of the prostate cancer prevention trial. BJU Int 2003;92(7):667—71.</mixed-citation><mixed-citation xml:lang="ru">Marberger M., Adolfsson J., Borkowski A. et al. The clinical implications of the prostate cancer prevention trial. BJU Int 2003;92(7):667—71.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">23. Roehrborn C.G. Prevention of prostate cancer with finasteride. N Engl J Med 2003;349:1569—72.</mixed-citation><mixed-citation xml:lang="ru">Roehrborn C.G. Prevention of prostate cancer with finasteride. N Engl J Med 2003;349:1569—72.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">24. Djavan B., Zlotta A., Schulman C. et al. Chemotherapeutic prevention studies of prostate cancer. J Urol 2004;171(2 Pt 2):S10—3.</mixed-citation><mixed-citation xml:lang="ru">Djavan B., Zlotta A., Schulman C. et al. Chemotherapeutic prevention studies of prostate cancer. J Urol 2004;171(2 Pt 2):S10—3.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">25. Algaba F., Epstein J.I., Aldape H.C. et al. Workgroup 5: Assessment of prostate carcinoma in core needle biopsy — definition of minimal criteria for the diagnosis of cancer in biopsy material. Cancer 1996;78: 376—81.</mixed-citation><mixed-citation xml:lang="ru">Algaba F., Epstein J.I., Aldape H.C. et al. Workgroup 5: Assessment of prostate carcinoma in core needle biopsy — definition of minimal criteria for the diagnosis of cancer in biopsy material. Cancer 1996;78: 376—81.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">26. Bostwick D.G., Qian J., Civantos F. et al. Does finasteride alter the pathology of the prostate and cancer grading? Clin Prostate Cancer 2004;2:228—35.</mixed-citation><mixed-citation xml:lang="ru">Bostwick D.G., Qian J., Civantos F. et al. Does finasteride alter the pathology of the prostate and cancer grading? Clin Prostate Cancer 2004;2:228—35.</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">27. Canby-Haginoa E., Hernandezb J., Branda T.C., Thompson I. Looking back at PCPT: looking forward to new paradigms in prostate cancer screening and prevention. Eur Urol 2007;51(1):27—33.</mixed-citation><mixed-citation xml:lang="ru">Canby-Haginoa E., Hernandezb J., Branda T.C., Thompson I. Looking back at PCPT: looking forward to new paradigms in prostate cancer screening and prevention. Eur Urol 2007;51(1):27—33.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">28. Klein E.A., Thompson I.M., Klein E.A., Thompson I.M. Update on chemoprevention of prostate cancer. Curr Opin Urol 2004;14:143—9.</mixed-citation><mixed-citation xml:lang="ru">Klein E.A., Thompson I.M., Klein E.A., Thompson I.M. Update on chemoprevention of prostate cancer. Curr Opin Urol 2004;14:143—9.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">29. Gomella L.G. Chemoprevention using dutasteride: the REDUCE trial. Curr Opin Urol 2005;15:29—32.</mixed-citation><mixed-citation xml:lang="ru">Gomella L.G. Chemoprevention using dutasteride: the REDUCE trial. Curr Opin Urol 2005;15:29—32.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
