Cancer UrologyCancer UrologyОнкоурология1726-97761996-1812Publishing House ABV Press109010.17650/1726-9776-2007-3-1-65-68DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. PROSTATE CANCERДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак предстательной железыExpression of human interleukin-6 and its viral homologue in prostate cancer tissueЭкспрессия интерлейкина-6 человека и его вирусного гомолога в ткани рака предстательной железыVeliyevYе. I.ВелиевЕ. И.
Russian Federation

Department of Urology and Surgical Andrology

Кафедра урологии и хирургической андрологии

RybalchenkoA. V.РыбальченкоА. В.
Russian Federation

Department of Urology and Surgical Andrology

Кафедра урологии и хирургической андрологии

ShirokovD. A.ШироковД. А.
Russian Federation

Laboratory of Immunology of Hemopoiesis

Лаборатория иммунологии гемопоэза

TupitsynN. N.ТупицынН. Н.
Russian Federation

Laboratory of Immunology of Hemopoiesis

Лаборатория иммунологии гемопоэза

Russian Medical Academy of Postgraduate EducationРМАПОN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical SciencesГУ РОНЦ им. Н.Н.Блохина РАМН300320073165681502202015022020https://oncourology.abvpress.ru/oncur/article/view/1090

Human interleukin-6 (IL-6) is of considerable importance in the pathogenesis of prostate cancer (PC). Prostatic cells are also known to be a reservoir for human herpesvirus 8 type (HHV-8). Due to the findings that HHV-8 had a homologue of human IL-6, viral IL-6, it seemed interesting to study the expression of these two cytokines in the tumor tissue of patients with PC. The expression of IL-6 mRNA was found in 70% of the patients. That of viral IL-6 was not detected in this disease. Nevertheless, a genetic HHV-8 material was ascertained in the tumor tissue of 2 patients with PC.

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