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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1048</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2008-4-4-74-79</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. URINARY BLADDER CANCER</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак мочевого пузыря</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Gemcitabine (Citochem) in the treatment of advanced transitional cell bladder cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Гемцитабин (Цитогем®) в лечении распространенного переходно-клеточного рака мочевого пузыря</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Matveyev</surname><given-names>V. B.</given-names></name><name xml:lang="ru"><surname>Матвеев</surname><given-names>В. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of urology</p><p>Moscow</p></bio><bio xml:lang="ru"><p>Отделение урологии</p><p>г. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volkova</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Волкова</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of urology</p><p>Moscow</p></bio><bio xml:lang="ru"><p>Отделение урологии</p><p>г. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Enterprise N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">ГУ РОНЦ им. Н.Н. Блохина РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2008-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2008</year></pub-date><volume>4</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>74</fpage><lpage>79</lpage><history><date date-type="received" iso-8601-date="2020-02-13"><day>13</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-13"><day>13</day><month>02</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1048">https://oncourology.abvpress.ru/oncur/article/view/1048</self-uri><abstract xml:lang="en"><p>Citochem is an effective and safe medication: main active substrate of the agent is gemcitabine. Citochem in combination with cisplatin provides satisfactory efficacy without high toxicity of treatment in patients with advanced transitional cell bladder cancer and can be recommended for use in clinical practice of oncourology.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Huang P., Chubb S., Hertel L.W. et al. Action of 2’,2’-difluorodeoxycytidine on DNA synthesis. Cancer Res 1991;51(22):6110—7.</mixed-citation><mixed-citation xml:lang="ru">Huang P., Chubb S., Hertel L.W. et al. Action of 2’,2’-difluorodeoxycytidine on DNA synthesis. Cancer Res 1991;51(22):6110—7.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. 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