<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Cancer Urology</journal-id><journal-title-group><journal-title xml:lang="en">Cancer Urology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкоурология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9776</issn><issn publication-format="electronic">1996-1812</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1038</article-id><article-id pub-id-type="doi">10.17650/1726-9776-2008-4-4-53-56</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. PROSTATE CANCER</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ МОЧЕПОЛОВОЙ СИСТЕМЫ. Рак предстательной железы</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The role of triptorelin (Diphereline) in the treatment of prostate cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Роль трипторелина (Диферелин) в лечении рака предстательной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Matveyev</surname><given-names>B. P.</given-names></name><name xml:lang="ru"><surname>Матвеев</surname><given-names>Б. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Enterprise N.N. Blokhin Russian Cancer Research Center of Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">ГУ РОНЦ им. Н.Н.Блохина РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2008-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2008</year></pub-date><volume>4</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>53</fpage><lpage>56</lpage><history><date date-type="received" iso-8601-date="2020-02-13"><day>13</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-13"><day>13</day><month>02</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncourology.abvpress.ru/oncur/article/view/1038">https://oncourology.abvpress.ru/oncur/article/view/1038</self-uri><abstract xml:lang="en"><p>Efficacy and safety issues of triptorelin (Diphereline) use in the treatment of patients with prostate cancer are addressed. Several clinical studies of efficacy of treatment with triptoreline both in mono-regimen and combined with other drugs are discussed.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Аксель Е.М. Заболеваемость злокачественными новообразованиями мочевых и мужских половых органов в России в 2003 г. Онкоурология 2005;(1):6—9.</mixed-citation><mixed-citation xml:lang="ru">Аксель Е.М. Заболеваемость злокачественными новообразованиями мочевых и мужских половых органов в России в 2003 г. Онкоурология 2005;(1):6—9.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Minkov N.K., Zozikov B.I., Yaneva Z., Uldry P.A. A phase II trial with new triptorelin sustained release formulations in prostatic carcinoma. Int Urol Nephrol 2001;33(2):379—83.</mixed-citation><mixed-citation xml:lang="ru">Minkov N.K., Zozikov B.I., Yaneva Z., Uldry P.A. A phase II trial with new triptorelin sustained release formulations in prostatic carcinoma. Int Urol Nephrol 2001;33(2):379—83.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Bouchot O., Soret J.Y., Jacqmin D. et al. Three-month sustained-release form of triptorelin in patients with advanced prostatic adenocarcinoma: results of an open pharmacodynamic and pharmacokinetic multicenter study. Horm Res 1998;50(2):89—93.</mixed-citation><mixed-citation xml:lang="ru">Bouchot O., Soret J.Y., Jacqmin D. et al. Three-month sustained-release form of triptorelin in patients with advanced prostatic adenocarcinoma: results of an open pharmacodynamic and pharmacokinetic multicenter study. Horm Res 1998;50(2):89—93.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Klippel K.F., Winkler C.J., Jocham D. et al. Effectiveness and tolerance of 1 dosage forms (subcutaneous and intramuscular) of decapeptyl depot in patients with advanced prostate carcinoma. Urologe A 1999;38(3):270—5.</mixed-citation><mixed-citation xml:lang="ru">Klippel K.F., Winkler C.J., Jocham D. et al. Effectiveness and tolerance of 1 dosage forms (subcutaneous and intramuscular) of decapeptyl depot in patients with advanced prostate carcinoma. Urologe A 1999;38(3):270—5.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Gonzalez-Barcena D., Perez-Sanchez P.L., Graef A. et al. Inhibition of the pituitary-gonadal axis by a single intramuscular administration of D-Trp-6-LH-RH (decapeptyl) in a sustained-release formulation in patients with prostatic carcinoma. Prostate 1989;14(4):291—300.</mixed-citation><mixed-citation xml:lang="ru">Gonzalez-Barcena D., Perez-Sanchez P.L., Graef A. et al. Inhibition of the pituitary-gonadal axis by a single intramuscular administration of D-Trp-6-LH-RH (decapeptyl) in a sustained-release formulation in patients with prostatic carcinoma. Prostate 1989;14(4):291—300.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Labrie F., Dupont A., Belanger A. et al. Long term treatment with luteinising hormone releasing hormone agonists and maintenance of serum testosterone to castration concentrations. Br Med J (Clin Res Ed) 1985 10;291(6492):369—70.</mixed-citation><mixed-citation xml:lang="ru">Labrie F., Dupont A., Belanger A. et al. Long term treatment with luteinising hormone releasing hormone agonists and maintenance of serum testosterone to castration concentrations. Br Med J (Clin Res Ed) 1985 10;291(6492):369—70.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Seppelt U., Bertermann H., Saerbeck C. Decapeptyl (D-Trp6-LH-RH) in the therapy of prostatic cancer with reference to the intramuscular administration of a depot preparation. Urologe A 1986;25(5):298—301.</mixed-citation><mixed-citation xml:lang="ru">Seppelt U., Bertermann H., Saerbeck C. Decapeptyl (D-Trp6-LH-RH) in the therapy of prostatic cancer with reference to the intramuscular administration of a depot preparation. Urologe A 1986;25(5):298—301.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Boccardo F., Decensi A., Guarneri D. et al. Long-term results with a long-acting formulation of D-TRP-6 LH-RH in patients with prostate cancer: an Italian prostatic cancer project (P.O.N.CA.P.) study. Prostate 1987;11(3):243—55.</mixed-citation><mixed-citation xml:lang="ru">Boccardo F., Decensi A., Guarneri D. et al. Long-term results with a long-acting formulation of D-TRP-6 LH-RH in patients with prostate cancer: an Italian prostatic cancer project (P.O.N.CA.P.) study. Prostate 1987;11(3):243—55.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Roger M., Duchier J., Lahlou N., Schally A.V. Treatment of prostatic cancers by periodic administration of a delayedrelease preparation of D-Trp(6)-LHRH. Ann Urol (Paris) 1986;20(2):109—12.</mixed-citation><mixed-citation xml:lang="ru">Roger M., Duchier J., Lahlou N., Schally A.V. Treatment of prostatic cancers by periodic administration of a delayedrelease preparation of D-Trp(6)-LHRH. Ann Urol (Paris) 1986;20(2):109—12.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Dupont A., Cusan L., Gomez J.L. et al. Combination therapy with flutamide and the LHRH agonist [D-Trp6, des-Gly-NH(2)10]LHRH ethylamide in stage C prostatic carcinoma. Br J Urol 1993;72(5 Pt 1):629—34.</mixed-citation><mixed-citation xml:lang="ru">Dupont A., Cusan L., Gomez J.L. et al. Combination therapy with flutamide and the LHRH agonist [D-Trp6, des-Gly-NH(2)10]LHRH ethylamide in stage C prostatic carcinoma. Br J Urol 1993;72(5 Pt 1):629—34.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Steg A., Chiche R., Boccon-Gibod L., Debre B. Treatment of advanced prostatic cancer with a gonadorelin agonist, D-Trp6-LHRH. 41 cases. Presse Med 1985;14(40):2045—8.</mixed-citation><mixed-citation xml:lang="ru">Steg A., Chiche R., Boccon-Gibod L., Debre B. Treatment of advanced prostatic cancer with a gonadorelin agonist, D-Trp6-LHRH. 41 cases. Presse Med 1985;14(40):2045—8.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Gonzalez-Barcena D., Perez-Sanchez P., Ureta-Sanchez S. et al. Treatment of advanced prostatic carcinoma with D-Trp-6-LH-RH. Prostate 1985;7(1):21—30.</mixed-citation><mixed-citation xml:lang="ru">Gonzalez-Barcena D., Perez-Sanchez P., Ureta-Sanchez S. et al. Treatment of advanced prostatic carcinoma with D-Trp-6-LH-RH. Prostate 1985;7(1):21—30.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Mathe G., Misset J.L., Vovan M.L., Machover D. Advanced cancer of the prostate. Treatment with an LH-RH agonist, D-Trp-6-LH-RH. Bull Cancer 1986;73(1):31—5.</mixed-citation><mixed-citation xml:lang="ru">Mathe G., Misset J.L., Vovan M.L., Machover D. Advanced cancer of the prostate. Treatment with an LH-RH agonist, D-Trp-6-LH-RH. Bull Cancer 1986;73(1):31—5.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Parmar H., Edwards L., Phillips R.H. et al. Orchiectomy versus long-acting D-Trp-6-LHRH in advanced prostatic cancer. Br J Urol 1987;59(3):248—54.</mixed-citation><mixed-citation xml:lang="ru">Parmar H., Edwards L., Phillips R.H. et al. Orchiectomy versus long-acting D-Trp-6-LHRH in advanced prostatic cancer. Br J Urol 1987;59(3):248—54.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Mathe G., Schally A.V., Comaru-Schally A.M. et al. Phase II trial with D-Trp-6-LH-RH in prostatic carcinoma: comparison with other hormonal agents. Prostate 1986;9(4):327—42.</mixed-citation><mixed-citation xml:lang="ru">Mathe G., Schally A.V., Comaru-Schally A.M. et al. Phase II trial with D-Trp-6-LH-RH in prostatic carcinoma: comparison with other hormonal agents. Prostate 1986;9(4):327—42.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Maillefert J.F., Sibilia J., Michel F. et al. Bone mineral density in men treated with synthetic gonadotropin-releasing hormone agonists for prostatic carcinoma. J Urol 1999;161(4):1219—22.</mixed-citation><mixed-citation xml:lang="ru">Maillefert J.F., Sibilia J., Michel F. et al. Bone mineral density in men treated with synthetic gonadotropin-releasing hormone agonists for prostatic carcinoma. J Urol 1999;161(4):1219—22.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
