Bladder cancer: what’s new in 2017
- Authors: Karyakin O.B.1, Kaprin A.D.2
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Affiliations:
- A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia
- National Medical Research Center of Radiology, Ministry of Health of Russia
- Issue: Vol 14, No 1 (2018)
- Pages: 157-165
- Section: REVIEW
- Published: 30.03.2018
- URL: https://oncourology.abvpress.ru/oncur/article/view/790
- DOI: https://doi.org/10.17650/1726-9776-2018-14-1-157-165
- ID: 790
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Abstract
Treatment of bladder cancer has been a complicated problem. Low survival for regional and metastatic disease remains. In recent years, the efforts of doctors, biologists, diagnosticians were aimed at development of new technologies in these spheres and improvement of treatment results for this pathology. In this review, current views on diagnosis, the role of repeated surgical interventions in non-muscle-invasive bladder cancer, etc. are presented. Advances in molecular biology allowed to differentiate subtypes of urothelial bladder cancer. Importantly, the results of biomolecular studies allowed to identify different responses to drug treatment. Moreover, in some cases these results have a follow-up period of up to 3 years. Based on other data characterizing the tumor, the effectiveness of new drugs for treatment of regional, metastatic and post-cisplatin therapy bladder cancer was evaluated. These results allow to hope for increased life span and quality of life for patients with this severe disease.
About the authors
O. B. Karyakin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia
Author for correspondence.
Email: Karyakin@mrrc.obninsk.ru
ORCID iD: 0000-0002-6112-2840
4 Korolyova St., Obninsk 249031
Russian FederationA. D. Kaprin
National Medical Research Center of Radiology, Ministry of Health of Russia
Email: Karyakin@mrrc.obninsk.ru
ORCID iD: 0000-0001-8784-8415
3 2nd Botkinskiy Proezd, Moscow 125284
Russian FederationReferences
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