Clinical features and results of surgical treatment of bilateral renal cancer

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Abstract

Renal cancer morbidity grows in most of the developed countries. Incidence of bilateral renal cell carcinoma, per various authors, amounts  to 2–6 % of all cases of this disease. The study included 160 patients with bilateral kidney cancer who received surgical treatment  at the N.N. Blokhin National Medical Research Center of Oncology in the period from 1996 to 2014. Median follow-up duration for all patients included in the analysis was 81.05 ± 46.7 months. In our study, the groups for synchronous and metachronous cancer were equal (n = 80) and constituted 3.5 % of all cases of kidney cancer. For synchronous and metachronous cancer types, the most common concomitant disease was arterial hypertension. The most common morphological variant for the first, as well as the second, kidney tumor was clear cell carcinoma. Smoking and ischemic heart disease as a concomitant pathology negatively affected relapse-free and overall survival. Overall 5-year survival for synchronous renal cancer was 84.4 ± 4.2 %, for metachronous – 64.8 ± 9.3 %.

About the authors

M. I. Komarov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Author for correspondence.
Email: 0050037@mail.ru
ORCID iD: 0000-0002-3670-0880

24 Kashirskoe Shosse, Moscow 115478

Russian Federation

V. B. Matveev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: vsevolodmatveev@mail.ru
ORCID iD: 0000-0001-7748-9527

24 Kashirskoe Shosse, Moscow 115478

Russian Federation

L. G. Zhukova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

24 Kashirskoe Shosse, Moscow 115478

Russian Federation

I. G. Komarov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-3495-5521

24 Kashirskoe Shosse, Moscow 115478

Russian Federation

V. A. Chernyaev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

24 Kashirskoe Shosse, Moscow 115478

Russian Federation

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