Clinical case of patient with ovarian cancer: possibilities of surgical treatment

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  • Authors: Alekseyev B.Y.1,2,3, Petrov L.О.1,4, Krashennikov А.А.1,4, Romikh V.V.5,3, Kaprin A.D.1,2,3
  • Affiliations:
    1. Moscow Scientific Research Institute of Oncology named after P.A. Herzen - branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation
    2. 3 2nd Botkinsky Pr., Moscow, 125284, Russia Scientific Research Institute of Urology and Interventional Radiology named after N.A. Lopatkin – branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation
    3. 51 3rd Parkovaya St., Moscow, 105425, Russia
    4. 3 2nd Botkinsky Pr., Moscow, 125284, Russia
    5. Scientific Research Institute of Urology and Interventional Radiology named after N.A. Lopatkin – branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation
  • Issue: Vol 11, No 4 (2015)
  • Pages: 96-101
  • Section: CLINICAL CASE
  • Published: 30.12.2015
  • URL: https://oncourology.abvpress.ru/oncur/article/view/475
  • DOI: https://doi.org/10.17650/1726-9776-2015-11-4-96-101
  • ID: 475

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Abstract

Ovarian cancer (OC) occupies the third place in the structure of gynecological malignancies and it’s still known for its high mortality rate. Therefore this disease remains one of the actual problems in modern oncology. The standard of care for patients with OC consists of primary surgery, followed by platinum-based chemotherapy in a case of the disease recurrence. These combined chemotherapy regimens allow to make significant improvement in survival rates in patients with OC. Surgery is another treatment option which can be applied in patients with recurrent OC including disease recurrence after prior chemotherapy. This method enables to make considerable improvement in survival for this certain group of patients.

We report a clinical case of young patient suffering from recurrent OC. The disease was initially diagnosed in 2001. After that the patient underwent several types of surgery and multiple courses of polychemotherapy. Detection of disease recurrence in 2013 required to conduct a very complicated surgical treatment. Currently this patient is under active follow-up with no signs of disease progression or disease recurrence. Application of enterocystoplasty technique (bladder augmentation using bowel segments) in reconstruction of the urinary tract in this particular case enabled to preserve the quality of patient’s life as well as to conduct radical surgery. In order to reduce artificial bladder activity, reduce/eliminate urinary incontinence and improve the quality of patient’s life botulinum toxin A was injected into the bladder wall. The effect of this injection was positive. To sum up, teamwork between the members of urology and oncology departments done in time allowed to provide complete urologic help which included examination with the use of modern highly technological equipment and treatment followed by methods of neurological rehabilitation. All these led to significant improvement of the quality of the patient’s life.

About the authors

B. Ya. Alekseyev

Moscow Scientific Research Institute of Oncology named after P.A. Herzen - branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 3 2nd Botkinsky Pr., Moscow, 125284, Russia
Scientific Research Institute of Urology and Interventional Radiology named after N.A. Lopatkin – branch of a State Budget Institution
“The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 51 3rd Parkovaya St., Moscow, 105425, Russia

Email: byalekseev@mail.ru
Д.м.н., профессор. Заместитель генерального директора по науке ФГБУ «НМИРЦ» Минздрава России. Заместитель директора «НИИ урологии и интервенционной урологии им. Н.А. Лопаткина» - филиала ФГБУ «НМИРЦ» Минздрава России. Ученый секретарь Российского общества онкоурологов. Russian Federation

L. О. Petrov

Moscow Scientific Research Institute of Oncology named after P.A. Herzen - branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 3 2nd Botkinsky Pr., Moscow, 125284, Russia

Email: leonid_petrov@mail.ru
Научный сотрудник отделения абдоминальной онкологии МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИРЦ» Минздрава России Russian Federation

А. А. Krashennikov

Moscow Scientific Research Institute of Oncology named after P.A. Herzen - branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 3 2nd Botkinsky Pr., Moscow, 125284, Russia

Author for correspondence.
Email: krush07@yandex.ru

Младший научный сотрудник отделения онкоурологии МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИРЦ» Минздрава России

Russian Federation

V. V. Romikh

Scientific Research Institute of Urology and Interventional Radiology named after N.A. Lopatkin – branch of a State Budget Institution
“The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 51 3rd Parkovaya St., Moscow, 105425, Russia

Email: vromikh@yandex.ru
Заведующая лабораторией уродинамических исследований, Russian Federation

A. D. Kaprin

Moscow Scientific Research Institute of Oncology named after P.A. Herzen - branch of a State Budget Institution “The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 3 2nd Botkinsky Pr., Moscow, 125284, Russia
Scientific Research Institute of Urology and Interventional Radiology named after N.A. Lopatkin – branch of a State Budget Institution
“The National Medical Radiological Center” of the Ministry of Health of the Russian Federation; 51 3rd Parkovaya St., Moscow, 105425, Russia

Email: mnioi@mail.ru
Д.м.н., профессор, член-корреспондент РАМН, генеральный директор ФГБУ «НМИРЦ» Минздрава России Russian Federation

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