Experience with one-stage operations for bilateral nephroblastoma

Cover Page

Cite item

Full Text

Abstract

The paper describes the personal experience with one-stage operations for bilateral nephroblastoma (BN) in children.
In 2000 to 2012, the Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute, performed one-stage surgical interventions in 21 (26.2 %) children with BN. Their age ranged from 10 months to 5 years. The one-stage surgery as bilateral nephrectomy was made in 9 children. Nephrectomy with one-stage resection of the contralateral kidney was carried out in 4 children; 4 patients underwent one-stage surgery as resection of one kidney and biopsy of the other and 4 patients had nephrectomy and biopsy of the second kidney.
BN is a rare disease as suggested by the data available in the world literature; each new report on patients with BN is of great scientific and practical interest. The rate of BN is 4 to 10 % of all kidney cancers in children. Synchronous and metachronous kidney injuries are encountered in 5–7 and 2–3 % of cases, respectively. Bilateral renal involvement is more commonly diagnosed in younger children. The major peak incidence of BN occurs from ages 3 to 5 years. The disease is rarely diagnosed in children above 10 years. Boys and girls are equally frequently ill. 

About the authors

A. P. Kazantsev

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Author for correspondence.
Email: oncoanat@mail.ru
Russian Federation

M. A. Rubansky

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

M. V. Rubanskaya

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

P. A. Kerimov

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

O. A. Kapkova

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

D. V. Rybakova

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

E. I. Boichenko

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

A. V. Khizhnikov

Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Institute; 23, Kashirskoe Shosse, Moscow 115 478, Russia

Russian Federation

References

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c)



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-36986 от  21.07.2009.