RECURRENT NON-MUSCLE INVASIVE BLADDER CANCER: POSSIBLE ENDOSCOPIC MODES TO SOLVE THE PROBLEM

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Abstract

The high rate of recurrences after transurethral resection of the bladder is a key problem in the treatment of patients with superficial tumors. The main reasons for the high rate of recurrences are diffuse urothelial neoplastic changes, cancer in situ, possible tumor cell implantation at surgery, and non-radical removal of a tumor itself. As of now, the most important ways of solving the problem, among which there are a lot of endoscopic modes, include increased radicality of primary tumor removal (bipolar electrosurgery, electrovaporization, laser resection and ablation), more precise intraoperative disease staging (Raman spectroscopy, optical coherence tomography), identification of invisible neoplasms by standard methods (photodynamic diagnosis, narrow-spectrum imaging), monitoring of primary tumor removal radicality (early recystoscopy and bladder biopsy), photodynamic therapy, urinary retention elimination, by saving the patient from infravesical obstruction, as well as urinary cytology, use of diagnostic markers (BTA test and others), adjuvant immunochemotherapy, radiotherapy, etc. By taking into account the data available in the literature and their findings, the authors consider possible ways of reducing the recurrence rate of superficial bladder carcinoma.

About the authors

A. G. Martov

City Clinical Urology Hospital Forty-Seven, Moscow Healthcare Department

Russian Federation

D. V. Ergakov

City Clinical Urology Hospital Forty-Seven, Moscow Healthcare Department

Russian Federation

A. S. Andronov

City Clinical Urology Hospital Forty-Seven, Moscow Healthcare Department

Author for correspondence.
Russian Federation

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