HORMONE AND RADIATION THERAPY IN HIGH- AND VERY HIGH-RISK PATIENTS WITH PROSTATE CANCER

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Abstract

The prevalence of prostate cancer (PC) is steadily growing every year. In the Russian Federation, its peak morbidity is in the age group of 70 years. Some patients refuse surgery or have contraindications because of comorbidity. Teleradiotherapy in combination with or without hormone therapy is an alternative treatment. The paper analyzes the authors’ results of treating high- and very high-risk patients with PC who received hormone and radiation therapy. The study retrospectively included the data of 132 patients who had been allocated to 3 groups according to the duration of adjuvant hormone therapy. The treatment results were assessed over a 5-year follow-up period according the following parameters: a lower decreased prostate-specific antigen (PSA) score, recurrence rate, and 5-year relapse-free survival determined the by PSA level.

About the authors

A. O. Karyakin

Medical Radiology Research Center, Ministry of Health of Russia, Obninsk

Author for correspondence.
Email: karyakin.alexey@gmail.com
Russian Federation

Yu. V. Gumenetskaya

Medical Radiology Research Center, Ministry of Health of Russia, Obninsk

Email: karyakin.alexey@gmail.com
Russian Federation

N. A. Gorban

Medical Radiology Research Center, Ministry of Health of Russia, Obninsk

Email: karyakin.alexey@gmail.com
Russian Federation

N. G. Minayeva

Medical Radiology Research Center, Ministry of Health of Russia, Obninsk

Email: karyakin.alexey@gmail.com
Russian Federation

O. B. Karyakin

Medical Radiology Research Center, Ministry of Health of Russia, Obninsk

Email: karyakin.alexey@gmail.com
Russian Federation

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