DIAGNOSTIC VALUE OF ANGIOGENESIS RATES IN RENAL-CELL CARCINOMA

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Abstract

The results of research in 130 patients with space-occupying lesions of kidneys treated in MCH n.a. S.R. Mirotvorcev were analysed. The diagnostic significance of metabolic tumor marker TuM2Pk, matrix metalloproteinases ММР-9, ММP-3, vascular endothelial growth factor (VEGF) and angiogenic cytokines (TNF-α, IL-8, IL-12) was evaluated. It was determined that VEGF detection in blood serum has the most important diagnostic value in differential diagnosis between renal tumor and renal cyst and in TNM staging.

About the authors

P. V. Glybochko

I.M. Sechenov First Moscow Medical University

Email: dendurnov@mail.ru
Russian Federation

N. B. Zacharova

State Medical Univercity n.a. V.I. Razumovskiy

Email: dendurnov@mail.ru
Russian Federation

A. N. Ponukalin

State Medical Univercity n.a. V.I. Razumovskiy

Email: dendurnov@mail.ru
Russian Federation

D. A. Durnov

State Medical Univercity n.a. V.I. Razumovskiy

Author for correspondence.
Email: dendurnov@mail.ru
Russian Federation

N. K. Shachpazyan

State Medical Univercity n.a. V.I. Razumovskiy

Email: dendurnov@mail.ru
Russian Federation

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