TERTIARY GLEASON GRADE ANDULTRASENSITIVE PROSTATE-SPECIFIC ANTIGEN LEVELS AS PROGNOSTIC FACTOR OF PROSTATE CANCER RECURRENCE

In the literature devoted to studying of prognostic factors of biochemical recurrence, the important place is taken away to discussion of ultra-sensitive PSA assays. Some researches have shown that the main value of ultrasensitive prostate-specific antigen (USPSA) level can be identification the patients of high risk group for progression and, as consequence, early revealing of disease recurrence. Subject of special studying is presence and definition of a tertiary Gleason grade (TGG) pattern in radical prostatectomy specimens. In the literature appears more and more the data that the TGG is associated with adverse pathology characteristics and a higher risk of biochemical recurrence.