Email this article Carcinosarcoma of the prostate: clinical observation and literature review
- Authors: Surkova V.S.1, Volchenko N.N.1, Lavrova A.M.1, Kosumova K.S.1, Khakimova G.G.2,3, Grebenkin M.V.4
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Affiliations:
- P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
- Tashkent City Branch of the Republican Specialized Scientific Practical Medical Center of Oncology and Radiology
- Department of Oncology, Children’s Oncology, Tashkent Pediatric Medical Institute
- N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
- Issue: Vol 19, No 3 (2023)
- Pages: 113-118
- Section: CLINICAL NOTES
- Published: 16.11.2023
- URL: https://oncourology.abvpress.ru/oncur/article/view/1663
- DOI: https://doi.org/10.17650/1726-9776-2023-19-3-113-118
- ID: 1663
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Abstract
Carcinosarcoma is a rare type of prostate neoplasms and accounts for less than 1 % of all malignant tumors of the prostate. This kind of tumor is characterized by the absence of prostate-specific antigen elevation in most cases, which leads to diagnosis of metastatic disease in a quarter of patients. Moreover, carcinosarcoma of the prostate has an extremely poor clinical prognosis. From the morphological point of a view, biphasicity is a typical feature for these tumors. As a rule, epithelial component is represented by poorly differentiated acinar adenocarcinoma. However, in some literature cases adenogenous component was represented by ductal or neuroendocrine carcinoma. Sarcoma component can be represented by any sarcoma type. Currently, pathogenesis of carcinosarcomas isn’t clear. In this report, we describe a clinical case of carcinosarcoma of the prostate in a 72-year-old male.
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About the authors
V. S. Surkova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Author for correspondence.
Email: sidorencko.tori@gmail.com
ORCID iD: 0000-0002-2674-0416
SPIN-code: 2191-3876
Viktoriya S. Surkova.
3 2nd Botkinskiy Proezd, Moscow 125284
Russian FederationN. N. Volchenko
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: mnioict@mail.ru
ORCID iD: 0000-0002-4873-4455
Nadezhda N. Volchenko.
3 2nd Botkinskiy Proezd, Moscow 125284
Russian FederationA. M. Lavrova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: anastasia.lavrova96@yandex.ru
ORCID iD: 0000-0002-8668-6108
SPIN-code: 6475-0073
Anastasiia M. Lavrova.
3 2nd Botkinskiy Proezd, Moscow 125284
Russian FederationKh. S. Kosumova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: kosumova92@mail.ru
ORCID iD: 0000-0002-1052-425X
SPIN-code: 5935-0652
Khadizhat S. Kosumova.
3 2nd Botkinskiy Proezd, Moscow 125284
Russian FederationG. G. Khakimova
Tashkent City Branch of the Republican Specialized Scientific Practical Medical Center of Oncology and Radiology; Department of Oncology, Children’s Oncology, Tashkent Pediatric Medical Institute
Email: hgg_doc@mail.ru
ORCID iD: 0000-0002-4970-5429
Gulnoz G. Khakimova.
1 Bagistan St., Tashkent 100070; 223 Bogishamol St., Tashkent 100140
UzbekistanM. V. Grebenkin
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: mv.grebenkin@yandex.ru
ORCID iD: 0000-0001-6415-9596
SPIN-code: 2982-5537
Maxim V. Grebenkin.
Build. 1, 51 3rd Parkovaya St., Moscow 105425
Russian FederationReferences
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