Adenomatoid tumor of the right adrenal gland masked as pheochromocytoma: clinical case
- Authors: Chuprina A.P.1, Bobin A.N.2, Pecherskaya M.S.2, Segedin R.E.2
-
Affiliations:
- S.M. Kirov Military Medical Academy, Ministry of Defense of Russia
- Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense of Russia
- Issue: Vol 19, No 4 (2023)
- Pages: 114-118
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. ADRENAL TUMORS
- Published: 29.12.2023
- URL: https://oncourology.abvpress.ru/oncur/article/view/1600
- DOI: https://doi.org/10.17650/1726-9776-2023-19-4-114-118
- ID: 1600
Cite item
Full Text
Abstract
According to summary autopsy data, the incidence of accidentally detected neoplasms of the adrenal glands is 6 %. Computed tomography performed for other reasons shows adrenal gland lesions in 4 % of cases. In diagnostic strategy for adrenal gland lesions, the most important factors to consider are hormonal activity and malignant potential. Moreover, absence of clinical manifestations for long periods of time and their mildness frequently lead to underestimation of the seriousness of the situation. Therefore, surgical treatment can be accompanied by multiple negative consequences. Literature describes cases accompanied by hypertensive crises which subsequently turned out to be hormonally inactive adenomas or adrenocortical carcinoma. The article describes a patient in whom hormonal activity masked an extremely rare benign tumor.
About the authors
A. P. Chuprina
S.M. Kirov Military Medical Academy, Ministry of Defense of Russia
Email: 2635825@mail.ru
ORCID iD: 0000-0002-3795-185X
6 Akademika Lebedeva St., Saint Petersburg 194044
Russian FederationA. N. Bobin
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense of Russia
Email: alebin@rambler.ru
ORCID iD: 0000-0002-7274-3431
3 Gospital’naya Ploshchad’, Moscow 105094
Russian FederationM. S. Pecherskaya
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense of Russia
Email: dr.uskova@mail.ru
ORCID iD: 0000-0003-0835-1545
3 Gospital’naya Ploshchad’, Moscow 105094
Russian FederationR. E. Segedin
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense of Russia
Author for correspondence.
Email: gvkg-seghedin@mail.ru
ORCID iD: 0000-0003-3261-3736
Roman E. Segedin
3 Gospital’naya Ploshchad’, Moscow 105094
Russian FederationReferences
- WHO Classification of Tumours. Available at: https://tumourclassification.iarc.who.int/chaptercontent/38/71.
- Lehman K.A., Zynger D.L. Adrenal gland & paraganglia. Available at: https://www.pathologyoutlines.com/topic/adrenaladenomatoid.html.
- Lack E.E. Tumors of the adrenal gland. In: Diagnostic Histopathology of Tumors. Ed.: C. Fletcher. 3rd edn. Churchill Livingstone Elsevier, 2007. Pp. 1099–122.
- Delellis R.A., Mangray S. The adrenal glands. In: Sternberg’s Diagnostic Surgical Pathology. Eds.: S.E. Mills, D. Carter, J. Greenson. 5th ed. Lippincott Williams and Wilkins, 2009. Pp. 545–567.
- Adem C., Schneider M., Hoang C. Pathologic quiz case: an unusual umbilical mass. Arch Pathol Lab Med 2003;127(7):303–4. doi: 10.5858/2003-127-e303-PQCAUU
- Kaplan M.A., Tazelaar H.D., Hayashi T. et al. Adenomatoid tumor of the pleura. Am J Surg Pathol 1996;20(10):1219–23. doi: 10.1097/00000478-199610000-00007
- Hanrahan J.B. A combined papillary mesothelioma and adenomatoid tumor of the omentum: report of the case. Cancer 1971;27: 109–14.
- Isotalo P.A., Nascimento A.G., Trastek V.F. et al. Extragenital adenomatoid tumor of a mediastinal lymph node. Mayo Clin Proc 2003;78(3):350–4. doi: 10.4065/78.3.350
- Benisch B.M. A retroperitoneal mesonephric cystadenoma with features of the adenomatoid tumor of the genital tract. J Urol 1973;110(1):44–6. doi: 10.1016/s0022-5347(17)60110-1
- Craig J.R., Hart W.R. Extargenital adenomatoid tumor: evidence for mesothelial theory of origin. Cancer 1979;43(5):1678–82. doi: 10.1002/1097-0142(197905)43:53.0.co;2-n
- Evans C.P., Vaccaro J.A., Storrs B.G. Suprarenal occurrence of an adenomatoid tumor. J Urol 1988;139(2):348–9. doi: 10.1016/s0022-5347(17)42410-4
- Hoffmann M., Yedibela S., Hohenberger W. et al. Adenomatoid tumor of the adrenal gland. Int J Surg 2008;6(6):485–7. doi: 10.1016/j.ijsu.2006.06.025
- Raaf H.N., Grant L.D., Santoscoy C. et al. Adenomatoid tumor of the adrenal gland: a report of four new cases and a review of the literature. Mod Pathol 1996;9(11):1046–51.
- https://www.nordiqc.org/epitope.php?id=77
- http://e-immunohistochemistry.info/web/Calretinin.htm
- http://www.microtesty.ru/catalog/calretinin_polyclonal_rabbit
- https://www.pathologyoutlines.com/topic/stainsD240.html
- Zhao M., Li C., Zheng J. et al. Cystic lymphangioma-like adenomatoid tumor of the adrenal gland: report of a rare case and review of the literature. Int J Clin Exp Pathol 2013;6(5):943–50.
- Golden A., Ash J.E. Adenomatoid tumors of the genital tract. Am J Pathol 1945;21(1):63–79.
- Mantero F., Terzolo M., Arnaldi G. et al. A survey on adrenal incidentaloma in Itali. Study Group on Adrenal Tumors of the Italian Society of Endocrinology. J Clin Endocrinol Metab 2000;85(2): 637–44. doi: 10.1210/jcem.85.2.6372
- Evans C.P., Vaccaro J.A., Storrs B.G., Christ P.J. Suprarenal occurrence of an adenomatoid tumor. J Urol 1988;139(2):348–9. doi: 10.1016/s0022-5347(17)42410-4
Supplementary files

