HYPERBARIC OXYGENATION IN THE TREATMENT OF LATE POSTRADIATION CYSTITIS

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Abstract

Radiotherapy (RT) alone or in combination with other treatment modalities is widely used in the treatment of urological and gynecological cancers. Despite the fact that there is continuous technical improvement of equipment and RT procedures, the frequency of complications due to this treatment option remains high in the early and late periods and generally requires complex and long-term care. One of the leading pathogenetic mechanisms responsible for the development of these complications is vascular endothelial damage and hence decreased blood and oxygen supply to the tissues of pelvic organs. Postradiation cystitis is one of the commonest complications of RT. Among various treatment modalities for postradiation hemorrhagic cystitis, hyperbaric oxygenation yielded good results particularly in cases of ineffective standard treatments.

About the authors

O. B. Loran

Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow

Author for correspondence.
Email: ples-doc@mail.ru
Russian Federation

L. A. Sinyakova

Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow

Email: ples-doc@mail.ru
Russian Federation

A. A. Mitrokhin

Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow

Email: ples-doc@mail.ru
Russian Federation

A. M. Plesovsky

Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow

Email: ples-doc@mail.ru
Russian Federation

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