NONINVASIVE DIAGNOSIS OF BLADDER CANCER BY CROSS-POLARIZATION OPTICAL COHERENCE TOMOGRAPHY: A BLIND STATISTICAL STUDY

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Abstract

Whether cross-polarization (CP) optical coherence tomography (OCT) could be used to detect early bladder cancer was ascertained; it was compared with traditional OCT within the framework of blind (closed) clinical statistical studies. One hundred and sixteen patients with local nonexophytic (flat) pathological processes of the bladder were examined; 360 CP OCT images were obtained and analyzed. The study used an OCT 1300-U CP optical coherence tomographer. CP OCT showed a high (94%) sensitivity and a high (84%) specificity in the identification of suspected nonexophytic areas in the urinary bladder.

About the authors

O. S. Streltsova

Department of Urology, Nizhny Novgorod State Medical Academy

Author for correspondence.
Email: strelzova_uro@mail.ru
Russian Federation

N. D. Gladkova

Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

E. B. Kiseleva

Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

M. M. Karabut

Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

E.A. Tararova

Department of Urology, Nizhny Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

К. E. Yunusova

Department of Pathoanatomy, Nizhny Novgorod State Medical Academy, Nizhny Novgorod

Email: strelzova_uro@mail.ru
Russian Federation

V. N. Krupin

Department of Urology, Nizhny Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

E. V. Zagainova

Department of Pathoanatomy, Nizhny Novgorod State Medical Academy, Nizhny Novgorod

Email: strelzova_uro@mail.ru
Russian Federation

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